ING4

Gene Symbol ING4
Entrez Gene 51147
Alt Symbol my036, p29ING4
Species Human
Gene Type protein-coding
Description inhibitor of growth family, member 4
Other Description brain my036 protein|candidate tumor suppressor p33 ING1 homolog|inhibitor of growth protein 4
Swissprots A4KYM6 Q9UNL4 Q9H3J0 A4KYM4 Q0EF63 Q4VBQ6 D3DUR8 Q96E15 Q0EF62
Accessions EAW88762 EAW88763 EAW88764 EAW88765 EAW88766 EAW88767 EAW88768 EAW88769 EAW88770 EAW88771 EAW88772 EAW88773 Q9UNL4 AB197695 BAF30477 AB197696 BAF30478 AB197697 BAF30479 AF063594 AAG43153 AF110645 AAD48585 AF156552 AAL79773 AK293169 BAG56713 AK303354 BAG64415 AK313621 AW515338 AW614868 BC007781 AAH07781 BC013038 AAH13038 BC095434 AAH95434 BG705367 BG718170 BM727982 BM922497 BP303219 BQ066994 EF152349 ABO61139 EF152350 ABO61140 EF152351 ABO61141 EF152352 ABO61142 JF432448 ADZ15665 XM_005253698 XP_005253755 XM_011520964 XP_011519266 XM_011520965 XP_011519267 XR_242982 XR_242983 NM_001127582 NP_001121054 NM_001127583 NP_001121055 NM_001127584 NP_001121056 NM_001127585 NP_001121057 NM_001127586 NP_001121058 NM_016162 NP_057246 NM_198287
Function Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1). {ECO:0000269|PubMed:12750254, ECO:0000269|PubMed:15029197, ECO:0000269|PubMed:15251430, ECO:0000269|PubMed:15528276, ECO:0000269|PubMed:15897452, ECO:0000269|PubMed:16387653}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15029197, ECO:0000269|PubMed:16973615}.

ING4 (A-8) - sc-376122 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ING4 (A-8): sc-376122. Western blot analysis of ING4 expression in non-transfected: sc-117752 (A) and human ING4 transfected: sc-111547 (B) 293T whole cell lysates.

ING4 (87.72) - sc-135743 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

ING4 (60.86) - sc-135742 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ING4 (60.86): sc-135742. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear and cytoplasmic localization.

ING4 (H-40) - sc-67326 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ING4 (H-40): sc-67326. Western blot analysis of ING4 expression in non-transfected: sc-117752 (A) and mouse ING4 transfected: sc-121066 (B) 293T whole cell lysates.

ING4 (F-17) - sc-55240 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ING4 (F-17): sc-55240. Western blot analysis of ING4 expression in NIH/3T3 nuclear extract (A) and RAW 264.7 (B) and PC-12 (C) whole cell lysates.

ING4 (T-15) - sc-50004 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ING4 (T-15): sc-50004. Western blot analysis of ING4 expression in non-transfected: sc-117752 (A) and mouse ING4 transfected: sc-121066 (B) 293T whole cell lysates.

ING4 (K-17) - sc-50003 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ING4 (E-18) - sc-55239 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ING4 (E-18): sc-55239. Western blot analysis of ING4 expression in non-transfected: sc-117752 (A) and mouse ING4 transfected: sc-121066 (B) 293T whole cell lysates.

Anti-ING4 antibody - ab3714 from Abcam

Prices $382.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Performed under reducing conditions.

Anti-ING4 antibody - ab90551 from Abcam

Host Mouse
Clonality Polyclonal
Anti-ING4 antibody (ab90551) at 1 µg/ml + A431 cell lysate at 50 µg

Anti-ING4 antibody - ab103631 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-ING4 antibody (ab103631) at 5 µg/ml + Human liver tissue lysate at 50 µg

Anti-ING4 antibody - ab113425 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ING4 antibody (ab113425) at 1/500 dilutionLane 1 : Human fetal liver lysateLane 2 : Human fetal kidney lysateLane 3 : Mouse kidney lysate

Anti-ING4 antibody - ab134718 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-ING4 antibody (ab134718) at 1/500 dilution + 293 cell extract at 30 µg

Anti-ING4 antibody [EP3804] - ab108621 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP3804
All lanes : Anti-ING4 antibody [EP3804] (ab108621) at 1/1000 dilutionLane 1 : 293T cell lysateLane 2 : T47-D cell lysateLane 3 : Jurkat cell lysateLysates/proteins at 10 µg per lane.

Anti-ING4 Antibody - LS-C334327 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using ING4 antibody.

Anti-ING4 Antibody (aa164-175) IHC-plus™ - LS-B386 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-ING4 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B386 concentration 5 ug/ml.

Anti-ING4 Antibody (aa110-159) IHC-plus™ - LS-B5821 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ING4 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5821 concentration 5 ug/ml.

Anti-ING4 Antibody (aa162-195) - LS-C344210 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical of paraffin-embedded H.pancreas section using ING4 Antibody. Antibody was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.

Anti-ING4 Antibody (aa163-174) - LS-C70699 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-ING4 Antibody (aa164-175) - LS-C191610 from LifeSpan Bioscience

Prices $560.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-ING4 Antibody - LS-C311289 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ING4 Antibody - LS-C308492 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ING4 Antibody - LS-C311288 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ING4 Antibody - LS-C341898 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ING4 Antibody (aa107-156) - LS-C199909 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from 293 cells, using ING4 antibody.
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