ING4

Gene Symbol ING4
Entrez Gene 51147
Alt Symbol my036, p29ING4
Species Human
Gene Type protein-coding
Description inhibitor of growth family, member 4
Other Description brain my036 protein|candidate tumor suppressor p33 ING1 homolog|inhibitor of growth protein 4
Swissprots A4KYM6 Q9UNL4 Q9H3J0 A4KYM4 Q0EF63 Q4VBQ6 D3DUR8 Q96E15 Q0EF62
Accessions EAW88762 EAW88763 EAW88764 EAW88765 EAW88766 EAW88767 EAW88768 EAW88769 EAW88770 EAW88771 EAW88772 EAW88773 Q9UNL4 AB197695 BAF30477 AB197696 BAF30478 AB197697 BAF30479 AF063594 AAG43153 AF110645 AAD48585 AF156552 AAL79773 AK293169 BAG56713 AK303354 BAG64415 AK313621 AW515338 AW614868 BC007781 AAH07781 BC013038 AAH13038 BC095434 AAH95434 BG705367 BG718170 BM727982 BM922497 BP303219 BQ066994 EF152349 ABO61139 EF152350 ABO61140 EF152351 ABO61141 EF152352 ABO61142 JF432448 ADZ15665 XM_005253698 XP_005253755 XM_011520964 XP_011519266 XM_011520965 XP_011519267 XR_242982 XR_242983 NM_001127582 NP_001121054 NM_001127583 NP_001121055 NM_001127584 NP_001121056 NM_001127585 NP_001121057 NM_001127586 NP_001121058 NM_016162 NP_057246 NM_198287
Function Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1). {ECO:0000269|PubMed:12750254, ECO:0000269|PubMed:15029197, ECO:0000269|PubMed:15251430, ECO:0000269|PubMed:15528276, ECO:0000269|PubMed:15897452, ECO:0000269|PubMed:16387653}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15029197, ECO:0000269|PubMed:16973615}.

ING4 CRISPR/Cas9 KO Plasmid (h) - sc-403707 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ING4 HDR Plasmid (h) - sc-403707-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ING4 Double Nickase Plasmid (h) - sc-403707-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ING4 Double Nickase Plasmid (h2) - sc-403707-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ING4 CRISPR Activation Plasmid (h) - sc-403707-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ING4 CRISPR Activation Plasmid (h2) - sc-403707-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ING4 Lentiviral Activation Particles (h) - sc-403707-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ING4 Lentiviral Activation Particles (h2) - sc-403707-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ING4 siRNA (h) - sc-60850 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ING4 shRNA Plasmid (h) - sc-60850-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ING4 shRNA (h) Lentiviral Particles - sc-60850-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ING4 RNAi - H00051147-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ING4 RNAi - H00051147-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN10673 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10673 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ING4 siRNA (Human) - CRH9562 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ING4 - MBS8211421 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ING4 (NM_016162.3) - SHH319505 from Creative biogene

Category siRNA
Species Reactivities Human

ING4 shRNA Plasmid (Human) - CHH9562 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ING4 miRNA 3'UTR clone - MiUTR3H-10064 from Creative biogene

Species Reactivities Human

ING4 miRNA 3'UTR clone - MiUTR3H-10065 from Creative biogene

Species Reactivities Human

ING4 miRNA 3'UTR clone - MiUTR3H-10066 from Creative biogene

Species Reactivities Human

ING4 miRNA 3'UTR clone - MiUTR3H-10067 from Creative biogene

Species Reactivities Human

ING4 miRNA 3'UTR clone - MiUTR3H-10068 from Creative biogene

Species Reactivities Human

ING4 miRNA 3'UTR clone - MiUTR3H-10069 from Creative biogene

Species Reactivities Human
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