Gene Symbol | GREM2 |
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Entrez Gene | 64388 |
Alt Symbol | CKTSF1B2, DAND3, PRDC |
Species | Human |
Gene Type | protein-coding |
Description | gremlin 2, DAN family BMP antagonist |
Other Description | DAN domain family member 3|cysteine knot superfamily 1, BMP antagonist 2|gremlin 2, cysteine knot superfamily, homolog|gremlin-2|protein related to DAN and cerberus |
Swissprots | Q9H772 Q86UD9 |
Accessions | EAW70083 EAW70084 Q9H772 AK024848 BAB15026 BC046632 AAH46632 BQ005641 XM_005273226 XP_005273283 XM_011544249 XP_011542551 NM_022469 NP_071914 |
Function | Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000305}. |
Human-GREM2-cDNA-Clone - DC07618 from Abgent, a WuXi AppTec company
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GREM2 - MBS1270081 from MyBioSource
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Human GREM2 cDNA clone(NM_022469.3) - CDFG003761 from Creative Biomart
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Human GREM2 ORF Clone(NM_022469.3) - CDCR307866 from Creative Biomart
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Human GREM2 ORF Clone(NM_022469.3) - CDCR307867 from Creative Biomart
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Human GREM2 ORF Clone(NM_022469.3) - CDCR307868 from Creative Biomart
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Human GREM2 ORF Clone(NM_022469.3) - CDCL165352 from Creative Biomart
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Human GREM2 ORF clone(NM_022469.3) - CDCL184471 from Creative Biomart
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Human GREM2 Gene cDNA Clone (full-length ORF Clone) expression ready, untagged - HG10283-M-N from Sino Biological
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Human Gremlin 2/GREM2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10283-M-F from Sino Biological
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Human GREM2 ORF clone(NM_022469.3) - CDCL184471 from Creative biogene
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Human GREM2 ORF Clone (BC046632) - CDCS415507 from Creative biogene
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Human GREM2 cDNA Clone(NM_022469.3) - CDFG003761 from Creative biogene
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Human Gremlin 2/GREM2 Gene ORF cDNA clone expression plasmid - HG10283-UT from Sino Biological
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