Gene Symbol | GREM2 |
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Entrez Gene | 64388 |
Alt Symbol | CKTSF1B2, DAND3, PRDC |
Species | Human |
Gene Type | protein-coding |
Description | gremlin 2, DAN family BMP antagonist |
Other Description | DAN domain family member 3|cysteine knot superfamily 1, BMP antagonist 2|gremlin 2, cysteine knot superfamily, homolog|gremlin-2|protein related to DAN and cerberus |
Swissprots | Q9H772 Q86UD9 |
Accessions | EAW70083 EAW70084 Q9H772 AK024848 BAB15026 BC046632 AAH46632 BQ005641 XM_005273226 XP_005273283 XM_011544249 XP_011542551 NM_022469 NP_071914 |
Function | Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000305}. |
Human GREM2 full length protein - ab163828 from Abcam
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Human GREM2 full length protein - ab156347 from Abcam
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Human GREM2 peptide - ab131363 from Abcam
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Recombinant Human PRDC/GREM2 Protein - H00064388-P01 from Novus Biologicals
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PRDC/GREM2 Protein - NBP2-23089 from Novus Biologicals
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Recombinant Human PRDC/GREM2 Protein - NBP1-99325 from Novus Biologicals
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PRDC/GREM2 Protein - NBP1-99662 from Novus Biologicals
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GREM2 recombinant protein - GTX65445 from GeneTex
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Recombinant Human PRDC/GREM2, CF - 8436-PR-050 from R&D Systems
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Human GREM2 protein - orb191131 from Biorbyt
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GREM2 Blocking Peptide - 33R-6009 from Fitzgerald
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GREM2 protein (His tag) - 80R-2754 from Fitzgerald
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Gremlin 2 protein - 30R-2673 from Fitzgerald
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Gremlin-2 / GREM2 (22-168, His-tag) - AR50873PU-N from Acris Antibodies
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Gremlin-2 / GREM2 (22-168, His-tag) - AR50873PU-S from Acris Antibodies
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Gremlin-2 / GREM2 - H00064388-P01 from Acris Antibodies
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GREM2, 22-168aa, Human, His tag, E.coli - 01-P2049 from ARP American Research Products
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GREM2 fusion protein - ag4854 from Proteintech Group
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Recombinant Human Gremlin 2, His-tagged - GREM2-2614H from Creative Biomart
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Recombinant Human gremlin 2, DAN family BMP antagonist, His-tagged - GREM2-534H from Creative Biomart
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Recombinant Gremlin 2 (GREM2) - RPN833Hu01 from Uscn Life Science Inc.
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Gremlin 2 Blocking Peptide - CBP3974 from Cohesion Biosciences
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Recombinant Gremlin 2 (GREM2) - RPN833Hu01 from Cloud-clone
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Recombinant Human Gremlin-2(GREM2) - CSB-YP887993HU CSB-EP887993HU CSB-BP887993HU CSB-MP887993HU from Cusabio
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GREM2, 22-168aa, Human, His tag, E.coli (Denatured) - ATGP2049 from ATGen
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