FKBP1A

Gene Symbol FKBP1A
Entrez Gene 2280
Alt Symbol FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE
Species Human
Gene Type protein-coding
Description FK506 binding protein 1A, 12kDa
Other Description 12 kDa FK506-binding protein|12 kDa FKBP|FK506 binding protein12|FK506-binding protein 1|FK506-binding protein 12|FK506-binding protein 1A (12kD)|FK506-binding protein, T-cell, 12-kD|FKBP12-Exip3|PPIase FKBP1A|calstabin 1|calstabin-1|immunophilin FKBP12|peptidyl-prolyl cis-trans isomerase FKBP1A|protein kinase C inhibitor 2|rotamase
Swissprots Q6LEU3 Q9H103 Q6FGD9 P20071 D3DVW6 Q9H566 Q4VC47 P62942
Accessions AAA58472 AAA58476 BAE44301 CAA39272 CAI95951 EAX10633 EAX10634 EAX10635 P62942 AA731598 AB241123 BAE94235 AB241124 BAE94236 AB241125 BAE94237 AF205192 AAF17608 AI753994 BC001925 AAH01925 BC005147 AAH05147 BC119732 AAI19733 BC119733 AAI19734 BT007066 AAP35729 BU540706 CA450516 CN426120 CR407613 CAG28541 CR542168 CAG46965 CX870892 D28444 BAA05810 DQ891819 ABM82745 M34539 AAA35844 X52220 CAA36462 NM_000801 NP_000792 NM_001199786 NP_001186715 NM_054014 NP_463460
Function Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. {ECO:0000269|PubMed:16720724, ECO:0000269|PubMed:9233797}.
Subcellular Location Cytoplasm.

FKBP1A overexpression lysate - LY409302 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

FKBP1A 293 Cell Lysate - 404928 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

FKBP1A 293 Cell Lysate - 400323 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

FKBP12 Overexpression Lysate (Native) - NBL1-10732 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: FKBP12 Overexpression Lysate (Adult Normal) [NBL1-10732] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for FKBP12.

FKBP12 Overexpression Lysate (Native) - NBL1-10733 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: FKBP12 Overexpression Lysate (Adult Normal) [NBL1-10733] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for FKBP12.

FKBP1A Over-expression Lysate Product - GWB-FE7E99 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

FKBP1A Over-expression Lysate Product - GWB-EE59F5 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human FKBP1A Knockdown Stable Cell Line - CSC-DC005762 from Creative biogene

Category Cell Line
Species Human
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