FKBP1A

Gene Symbol	FKBP1A
Entrez Gene	2280
Alt Symbol	FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE
Species	Human
Gene Type	protein-coding
Description	FK506 binding protein 1A, 12kDa
Other Description	12 kDa FK506-binding protein|12 kDa FKBP|FK506 binding protein12|FK506-binding protein 1|FK506-binding protein 12|FK506-binding protein 1A (12kD)|FK506-binding protein, T-cell, 12-kD|FKBP12-Exip3|PPIase FKBP1A|calstabin 1|calstabin-1|immunophilin FKBP12|peptidyl-prolyl cis-trans isomerase FKBP1A|protein kinase C inhibitor 2|rotamase
Swissprots	Q6LEU3 Q9H103 Q6FGD9 P20071 D3DVW6 Q9H566 Q4VC47 P62942
Accessions	AAA58472 AAA58476 BAE44301 CAA39272 CAI95951 EAX10633 EAX10634 EAX10635 P62942 AA731598 AB241123 BAE94235 AB241124 BAE94236 AB241125 BAE94237 AF205192 AAF17608 AI753994 BC001925 AAH01925 BC005147 AAH05147 BC119732 AAI19733 BC119733 AAI19734 BT007066 AAP35729 BU540706 CA450516 CN426120 CR407613 CAG28541 CR542168 CAG46965 CX870892 D28444 BAA05810 DQ891819 ABM82745 M34539 AAA35844 X52220 CAA36462 NM_000801 NP_000792 NM_001199786 NP_001186715 NM_054014 NP_463460
Function	Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. {ECO:0000269|PubMed:16720724, ECO:0000269|PubMed:9233797}.
Subcellular Location	Cytoplasm.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human FKBP12 full length protein - ab167985 from Abcam Category Protein Prices $410.00 Sizes 100 µg Source E. coli Species Human

Active human FKBP12 full length protein - ab85840 from Abcam Category Protein Prices $200.00, $706.00 Sizes 100 µg, 500 µg Source E. coli Species Human

FKBP12 peptide - ab4935 from Abcam Category Peptide Prices $181.00 Sizes 50 µg

Human FKBP12 full length protein - ab56524 from Abcam Category Protein Source E. coli Species Human

Human FKBP12 full length protein - ab193862 from Abcam Category Protein Source Mammalian Species Human

Human FKBP12 full length protein - ab61244 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human FKBP12 full length protein - ab83482 from Abcam Category Protein Source E. coli Species Human

Human FKBP12 peptide - ab25840 from Abcam Category Peptide

Mouse FKBP12 full length protein - ab201895 from Abcam Category Protein Source E. coli Species Mouse

FKBP1A / FKBP12 Antibody Blocking Peptide - LS-E9240 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FKBP1A / FKBP12 Antibody Blocking Peptide - LS-E23733 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FKBP1A / FKBP12 Antibody Blocking Peptide - LS-E23734 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human FKBP12 Protein - H00002280-P01 from Novus Biologicals Category Protein Prices $529.00 Sizes 25 µg Source Wheat Germ Species Human

FKBP12 Recombinant Protein - P3484 from Novus Biologicals Category Protein Prices $449.00 Sizes 100 µg Species Human

FKBP12-Antibody-Center-Blocking-Peptide - BP7756c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human FKBP12, CF - 3777-FK-100 from R&D Systems Category Protein Source E. coli-derived, Gly2-Glu108, with an N-terminal Met and 6-His tag

Recombinant human Peptidyl-prolyl cis-trans isomerase FKBP1A (OPCA00443) - OPCA00443 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

FKBP1A Protein (OPPA01685) - OPPA01685 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human FKBP1A protein - orb90093 from Biorbyt Category Protein Prices $170.00, $289.00, $451.00 Sizes 2 μg, 10 μg, 100 μg Source E.coli Species Human

Human FKBP1A protein - orb245121 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

FKBP1a /FKBP12 protein (His tag) - 80R-1130 from Fitzgerald Category Protein Prices $220.00 Sizes 100 µg Source E.coli

Human FKBP1A Protein - abx066667 from Abbexa Category Protein Source E.coli Species Human

FKBP1A / FKBP12 (1-108, His-tag) - AR09165PU-L from Acris Antibodies Category Protein Prices $695.00 Sizes 500 µg Source E. coli Species Human

FKBP1A / FKBP12 (1-108, His-tag) - AR09165PU-N from Acris Antibodies Category Protein Prices $305.00 Sizes 100 µg Source E. coli Species Human

FKBP1A / FKBP12 - H00002280-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

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