FKBP1A

Gene Symbol FKBP1A
Entrez Gene 2280
Alt Symbol FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE
Species Human
Gene Type protein-coding
Description FK506 binding protein 1A, 12kDa
Other Description 12 kDa FK506-binding protein|12 kDa FKBP|FK506 binding protein12|FK506-binding protein 1|FK506-binding protein 12|FK506-binding protein 1A (12kD)|FK506-binding protein, T-cell, 12-kD|FKBP12-Exip3|PPIase FKBP1A|calstabin 1|calstabin-1|immunophilin FKBP12|peptidyl-prolyl cis-trans isomerase FKBP1A|protein kinase C inhibitor 2|rotamase
Swissprots Q6LEU3 Q9H103 Q6FGD9 P20071 D3DVW6 Q9H566 Q4VC47 P62942
Accessions AAA58472 AAA58476 BAE44301 CAA39272 CAI95951 EAX10633 EAX10634 EAX10635 P62942 AA731598 AB241123 BAE94235 AB241124 BAE94236 AB241125 BAE94237 AF205192 AAF17608 AI753994 BC001925 AAH01925 BC005147 AAH05147 BC119732 AAI19733 BC119733 AAI19734 BT007066 AAP35729 BU540706 CA450516 CN426120 CR407613 CAG28541 CR542168 CAG46965 CX870892 D28444 BAA05810 DQ891819 ABM82745 M34539 AAA35844 X52220 CAA36462 NM_000801 NP_000792 NM_001199786 NP_001186715 NM_054014 NP_463460
Function Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. {ECO:0000269|PubMed:16720724, ECO:0000269|PubMed:9233797}.
Subcellular Location Cytoplasm.

FKBP12 CRISPR/Cas9 KO Plasmid (h) - sc-417531 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FKBP12 HDR Plasmid (h) - sc-417531-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FKBP12 Double Nickase Plasmid (h) - sc-417531-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FKBP12 Double Nickase Plasmid (h2) - sc-417531-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FKBP12 CRISPR Activation Plasmid (h) - sc-417531-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FKBP12 CRISPR Activation Plasmid (h2) - sc-417531-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FKBP12 Lentiviral Activation Particles (h) - sc-417531-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FKBP12 Lentiviral Activation Particles (h2) - sc-417531-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FKBP12 siRNA (h) - sc-35378 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FKBP12 shRNA Plasmid (h) - sc-35378-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FKBP12 shRNA (h) Lentiviral Particles - sc-35378-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FKBP12 RNAi - H00002280-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

FKBP12 RNAi - H00002280-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU106961 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8710 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8710 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

FKBP1A siRNA (Human) - CRH1594 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FKBP1A - MBS8224971 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FKBP1A (NM_000801.4) - SHH295202 from Creative biogene

Category siRNA
Species Reactivities Human

FKBP1A shRNA Plasmid (Human) - CHH1594 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FKBP1A miRNA 3'UTR clone - MiUTR3H-02186 from Creative biogene

Species Reactivities Human

FKBP1A miRNA 3'UTR clone - MiUTR3H-02187 from Creative biogene

Species Reactivities Human
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