PTPRR

Gene Symbol	PTPRR
Entrez Gene	5801
Alt Symbol	EC-PTP, PCPTP1, PTP-SL, PTPBR7, PTPRQ
Species	Human
Gene Type	protein-coding
Description	protein tyrosine phosphatase, receptor type, R
Other Description	Ch-1 PTPase\|NC-PTPCOM1\|R-PTP-R\|ch-1PTPase\|protein tyrosine phosphatase Cr1PTPase\|protein-tyrosine phosphatase NC-PTPCOM1\|protein-tyrosine phosphatase PCPTP1\|receptor-type tyrosine-protein phosphatase R
Swissprots	O00342 Q9UE65 Q15256 B2R5Z7 Q92682 F5GXR7 B7Z3J1
Accessions	AAG47642 EAW97255 EAW97256 Q15256 AK091647 AK295951 BAH12227 AK304457 BAH14192 AK304672 BAH14234 AK312376 BAG35294 BC072386 BC092469 AAH92469 BC110900 AAI10901 BC119777 AAI19778 BC122866 AAI22867 BX571751 CAE11876 CA435261 CR749836 CAH18692 D64053 BAA10930 DA329806 DC304601 DC421975 U42361 AAD09447 U77916 AAB54006 U77917 AAB54007 X82635 CAA57957 Z79693 CAB01957 XM_011538615 XP_011536917 XM_011538616 XP_011536918 XR_944652 NM_001207015 NP_001193944 NM_001207016 NP_001193945 NM_002849 NP_002840 NM_130846 NP_570897 NR_073474
Function	Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity). {ECO:0000250}.
Subcellular Location	Isoform Gamma: Cytoplasm, perinuclear region. Note=Locates to the perinuclear areas within the cytoplasm.
Tissue Specificity	Expressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate. Isoform alpha has been observed only in the brain. Isoform gamma is expressed in brain, placenta and uterus. Isoform delta is expressed in brain, kidney, placenta, prostate, small intestine and uterus. {ECO:0000269\|PubMed:10705342}.
Top Pathways	MAPK signaling pathway

PCPTP1 (C-18) - sc-68112 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

PCPTP1 (C-18): sc-68112. Immunoperoxidase staining of formalin fixed, paraffin-embedded human upper stomach tissue showing cytoplasmic staining of glandular cells.

PCPTP1 (H-44) - sc-366450 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

PCPTP1 (T-15) - sc-68114 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

PCPTP1 (V-15) - sc-68115 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-PCPTP1 antibody - ab12153 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-PCPTP1 antibody (ab12153) at 0.4 µg/mlLane 1 : 0.01µg PTP beta (PTP RB)Lane 2 : 0.01µg PTP epsilon (PTP RE)Lane 3 : 0.01µg LAR (PTP RF)Lane 4 : 0.01µg PTP gamma (PTP RG)Lane 5 : 0.01µg SAP1 (PTP RH)Lane 6 : 0.01µg DEP1 (PTP RJ)Lane 7 : 0.01µg PTP kappa (PTP RK)Lane 8 : 0.01µg PTPIA2 (PTP RN)Lane 9 : 0.01µg GLEPP1 (PTP RO)Lane 10 : 0.01µg PCPTP1 (PTP RR)Lane 11 : 0.01µg CD45 (PTP RC)SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab6721) at 0.2 µg/mlPerformed under reducing conditions.

Anti-PCPTP1 antibody - ab188794 from Abcam

Prices	$407.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry analysis of formalin/PFA-fixed paraffin-embedded human adrenal sections labeling Hypothetical protein DKFZp686K0257 using ab188794 at 10 µg/ml.

Anti-PCPTP1 antibody - ab172263 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-PCPTP1 antibody (ab172263) at 1 µg/mlLane 1 : PTPRR transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-PCPTP1 antibody [EPR13188] - ab180134 from Abcam

Prices	$357.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR13188

All lanes : Anti-PCPTP1 antibody [EPR13188] (ab180134) at 1/5000 dilutionLane 1 : Human cerebellum lysate at 20 µgLane 2 : Mouse brain lysate at 20 µgLane 3 : Rat brain lysate at 10 µgSecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-PCPTP1 antibody [T10-AF4H11] - ab88958 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	T10-AF4H11

All lanes : Anti-PCPTP1 antibody [T10-AF4H11] (ab88958) at 1/1000 dilutionLane 1 : Bosc23 cell lysate Lane 2 : Bosc23 cell lysate transfected with Myc/His/Tau (1-441aa)Lane 3 : Bosc23 cell lysate transfected with Myc/His/PCPTP1 (328-651aa)Lane 4 : Bosc23 cell lysate transfected with GFP-Ub+1

Anti-PTPRR Antibody (clone 6A6) - LS-C204189 from LifeSpan Bioscience

Prices	$465.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	6A6

Anti-PTPRR Antibody (clone 6A6) - LS-C122366 from LifeSpan Bioscience

Prices	$680.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	6A6

Anti-PTPRR Antibody (N-Terminus, AP) - LS-C281618 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-PTPRR Antibody (N-Terminus, APC) - LS-C281619 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-PTPRR Antibody (N-Terminus, Azide-free, HRP) - LS-C281620 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-PTPRR Antibody (N-Terminus, FITC) - LS-C281621 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-PTPRR Antibody (N-Terminus, Biotin) - LS-C281622 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-PTPRR Antibody (N-Terminus, PE) - LS-C281626 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-PTPRR Antibody - LS-C318565 from LifeSpan Bioscience

Prices	$305.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PTPRR Antibody (FITC) - LS-C318568 from LifeSpan Bioscience

Prices	$305.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PTPRR Antibody (HRP) - LS-C318566 from LifeSpan Bioscience

Prices	$305.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PTPRR Antibody (Biotin) - LS-C318569 from LifeSpan Bioscience

Prices	$305.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PTPRR Antibody (N-Terminus) - LS-C328387 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-PTPRR Antibody - LS-C332490 from LifeSpan Bioscience

Prices	$305.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PTPRR Antibody (aa107-156) - LS-C116297 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

PTPRR antibody LS-C116297 Western blot of COLO205 cell lysate.

Anti-PTPRR Antibody - LS-C109447 from LifeSpan Bioscience

Prices	$335.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Sample (30 ug of whole cell lysate). A: H1299. 7.5% SDS PAGE. PTPRR antibody diluted at 1:5000

Search more