PTPRR

Gene Symbol	PTPRR
Entrez Gene	5801
Alt Symbol	EC-PTP, PCPTP1, PTP-SL, PTPBR7, PTPRQ
Species	Human
Gene Type	protein-coding
Description	protein tyrosine phosphatase, receptor type, R
Other Description	Ch-1 PTPase|NC-PTPCOM1|R-PTP-R|ch-1PTPase|protein tyrosine phosphatase Cr1PTPase|protein-tyrosine phosphatase NC-PTPCOM1|protein-tyrosine phosphatase PCPTP1|receptor-type tyrosine-protein phosphatase R
Swissprots	O00342 Q9UE65 Q15256 B2R5Z7 Q92682 F5GXR7 B7Z3J1
Accessions	AAG47642 EAW97255 EAW97256 Q15256 AK091647 AK295951 BAH12227 AK304457 BAH14192 AK304672 BAH14234 AK312376 BAG35294 BC072386 BC092469 AAH92469 BC110900 AAI10901 BC119777 AAI19778 BC122866 AAI22867 BX571751 CAE11876 CA435261 CR749836 CAH18692 D64053 BAA10930 DA329806 DC304601 DC421975 U42361 AAD09447 U77916 AAB54006 U77917 AAB54007 X82635 CAA57957 Z79693 CAB01957 XM_011538615 XP_011536917 XM_011538616 XP_011536918 XR_944652 NM_001207015 NP_001193944 NM_001207016 NP_001193945 NM_002849 NP_002840 NM_130846 NP_570897 NR_073474
Function	Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity). {ECO:0000250}.
Subcellular Location	Isoform Gamma: Cytoplasm, perinuclear region. Note=Locates to the perinuclear areas within the cytoplasm.
Tissue Specificity	Expressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate. Isoform alpha has been observed only in the brain. Isoform gamma is expressed in brain, placenta and uterus. Isoform delta is expressed in brain, kidney, placenta, prostate, small intestine and uterus. {ECO:0000269|PubMed:10705342}.
Top Pathways	MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PTPRR 293T Cell Transient Overexpression Lysate(Denatured) - H00005801-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

PTPRR overexpression lysate - LY419077 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

PTPRR overexpression lysate - LY429118 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PTPRR 293 Cell Lysate - 404798 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

PCPTP1 Overexpression Lysate (Denatured) - H00005801-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

PCPTP1 Overexpression Lysate (Native) - NBL1-14987 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PTPRR Over-expression Lysate Product - GWB-5E3B43 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

PCPTP1 Overexpression Lysate (Native) - NBP2-10850 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

PCPTP1 Overexpression Lysate (Native) - NBP2-11323 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human PTPRR Knockdown Stable Cell Line - CSC-DC012728 from Creative biogene Category Cell Line Species Human

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