PTPRR

Gene Symbol	PTPRR
Entrez Gene	5801
Alt Symbol	EC-PTP, PCPTP1, PTP-SL, PTPBR7, PTPRQ
Species	Human
Gene Type	protein-coding
Description	protein tyrosine phosphatase, receptor type, R
Other Description	Ch-1 PTPase|NC-PTPCOM1|R-PTP-R|ch-1PTPase|protein tyrosine phosphatase Cr1PTPase|protein-tyrosine phosphatase NC-PTPCOM1|protein-tyrosine phosphatase PCPTP1|receptor-type tyrosine-protein phosphatase R
Swissprots	O00342 Q9UE65 Q15256 B2R5Z7 Q92682 F5GXR7 B7Z3J1
Accessions	AAG47642 EAW97255 EAW97256 Q15256 AK091647 AK295951 BAH12227 AK304457 BAH14192 AK304672 BAH14234 AK312376 BAG35294 BC072386 BC092469 AAH92469 BC110900 AAI10901 BC119777 AAI19778 BC122866 AAI22867 BX571751 CAE11876 CA435261 CR749836 CAH18692 D64053 BAA10930 DA329806 DC304601 DC421975 U42361 AAD09447 U77916 AAB54006 U77917 AAB54007 X82635 CAA57957 Z79693 CAB01957 XM_011538615 XP_011536917 XM_011538616 XP_011536918 XR_944652 NM_001207015 NP_001193944 NM_001207016 NP_001193945 NM_002849 NP_002840 NM_130846 NP_570897 NR_073474
Function	Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity). {ECO:0000250}.
Subcellular Location	Isoform Gamma: Cytoplasm, perinuclear region. Note=Locates to the perinuclear areas within the cytoplasm.
Tissue Specificity	Expressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate. Isoform alpha has been observed only in the brain. Isoform gamma is expressed in brain, placenta and uterus. Isoform delta is expressed in brain, kidney, placenta, prostate, small intestine and uterus. {ECO:0000269|PubMed:10705342}.
Top Pathways	MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PCPTP1 full length protein - ab132435 from Abcam Category Protein Source Wheat germ Species Human

Human PCPTP1 peptide - ab24482 from Abcam Category Peptide

PTPRR Antibody Blocking Peptide - LS-E16592 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PTPRR Antibody Blocking Peptide - LS-E16593 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PTPRR Antibody Blocking Peptide - LS-E9566 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PCPTP1 Protein - H00005801-P01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

PCPTP1 Peptide - P3242 from Novus Biologicals Category Peptide Species Human

PCPTP1-Antibody-N-term-Blocking-Peptide - BP8409a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human PTPRR protein - orb244831 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

PTPRR Blocking Peptide - 33R-8987 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PTPRR Blocking Peptide - 33R-6944 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PTPRR Blocking Peptide - 33R-6718 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PTPRR - H00005801-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

PTPRR - H00005801-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

PTPRR fusion protein - Ag12145 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human PTPRR, GST-tagged - PTPRR-2066H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human PTPRR - PTPRR-618H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant human PTPRR protein - CSB-EP624019HU CSB-BP624019HU CSB-MP624019HU from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

Recombinant human PTPRR protein - CSB-EP624019HU from Cusabio Category Protein Source E.coli Species Human

Recombinant Human Receptor-type tyrosine-protein phosphatase R(PTPRR) - CSB-YP624019HU CSB-BP624019HU CSB-MP624019HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

PTPRR (transcript variant 2) - TP311122 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

PTPRR (transcript variant 1) - TP312896 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

PCPTP1 Recombinant Protein Antigen - NBP1-84912PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PTPRQ Peptide, Human - M34GP12727H from Creative Peptides Category Peptide Source Synthetic. Species Human

PTPRR Peptide, Human - M34GP12728H from Creative Peptides Category Peptide Source Synthetic. Species Human

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