SRSF10

Gene Symbol	SRSF10
Entrez Gene	10772
Alt Symbol	FUSIP1, FUSIP2, NSSR, PPP1R149, SFRS13, SFRS13A, SRp38, SRrp40, TASR, TASR1, TASR2
Species	Human
Gene Type	protein-coding
Description	serine/arginine-rich splicing factor 10
Other Description	40 kDa SR-repressor protein|FUS interacting protein (serine-arginine rich) 1|FUS-interacting protein (serine-arginine rich) 2|SR splicing factor 10|TLS-associated SR protein|TLS-associated protein TASR|TLS-associated protein with SR repeats|TLS-associated protein with Ser-Arg repeats|TLS-associated serine-arginine protein 1|TLS-associated serine-arginine protein 2|neural-salient SR protein|protein phosphatase 1, regulatory subunit 149|serine-arginine repressor protein (40 kDa)|splicing factor SRp38|splicing factor, arginine/serine-rich 13|splicing factor, arginine/serine-rich 13A
Swissprots	A6NI42 Q96P17 Q5JRI4 Q5JRI2 B4DJP9 Q96G09 Q5JRI3 O75494 A6NIU7 Q5JRH9 O60572 Q5JRI0 A6NFM6
Accessions	AAL06098 AAL06099 AAL16666 CAE89263 CAE89624 CAF16752 EAW95103 EAW95104 EAW95105 EAW95106 EAW95107 O75494 AA808243 AF047448 AAC70918 AF067730 AAC26727 AF419331 AAL16665 AF449427 AAL57514 AK001286 BAA91601 AK001479 AK001656 BAG50956 AK054635 AK055311 BAG51498 AK093226 AK125834 BAG54253 AK222994 BAD96714 AK296175 BAG58911 AL133655 AY007101 AY150180 AAN65380 AY150181 AAN65381 BC001107 AAH01107 BC005039 AAH05039 BC010074 AAH10074 BC071575 AAH71575 BX648939 HQ448699 ADQ33177 NM_001191005 NP_001177934 NM_001191006 NP_001177935 NM_001191007 NP_001177936 NM_001191009 NP_001177938 NM_001300936 NP_001287865 NM_001300937 NP_001287866 NM_006625 NP_006616 NM_054016 NP_473357 NR_034035
Function	Splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing. Seems to interfere with the U1 snRNP 5'-splice recognition of SNRNP70. Required for splicing repression in M-phase cells and after heat shock. May be involved in regulation of alternative splicing in neurons, with isoform 1 acting as a positive and isoform 3 as a negative regulator. {ECO:0000269|PubMed:11684676, ECO:0000269|PubMed:12419250, ECO:0000269|PubMed:14765198}.
Subcellular Location	Nucleus speckle {ECO:0000269|PubMed:11684676}. Cytoplasm {ECO:0000269|PubMed:11684676}.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:11684676, ECO:0000269|PubMed:11891055}.
Top Pathways	Spliceosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FUSIP1 (T-16) - sc-131157 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

FUSIP1 (T-18) - sc-101132 from Santa Cruz Biotechnology Prices $295.00 Sizes 100 µg/ml Host Mouse Clonality Monoclonal

FUSIP1 (E-23) - sc-101961 from Santa Cruz Biotechnology Prices $279.00 Sizes 50 µg/0.5 ml Host Rabbit Clonality Polyclonal

Anti-FUSIP1 antibody - C-terminal - ab173216 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-SR Proteins antibody - ab56762 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-SRSF10 / FUSIP1 Antibody (Internal) - LS-C125635 from LifeSpan Bioscience Prices $485.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-SRSF10 / FUSIP1 Antibody (aa196-225, AP) - LS-C257426 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SRSF10 / FUSIP1 Antibody (aa196-225, APC) - LS-C257428 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SRSF10 / FUSIP1 Antibody (aa196-225, Biotin) - LS-C257429 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SRSF10 / FUSIP1 Antibody (aa196-225, FITC) - LS-C257430 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SRSF10 / FUSIP1 Antibody (aa196-225, Azide-free, HRP) - LS-C257432 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SRSF10 / FUSIP1 Antibody (aa196-225, PE) - LS-C257434 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SRSF10 / FUSIP1 Antibody (Internal) - LS-C141932 from LifeSpan Bioscience Prices $335.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-SRSF10 / FUSIP1 Antibody (aa176-225) - LS-C80396 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-SRSF10 / FUSIP1 Antibody (N-Terminus) - LS-C110554 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-SRSF10 / FUSIP1 Antibody (C-Terminus) - LS-C30364 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-SRSF10 / FUSIP1 Antibody (aa1-101, Azide-free) - LS-C327413 from LifeSpan Bioscience Host Mouse Clonality Monoclonal

Anti-SRSF10 / FUSIP1 Antibody (aa196-225) - LS-C321481 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SRSF10 / FUSIP1 Antibody (aa196-225) - LS-C159686 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-SRSF10 / FUSIP1 Antibody - LS-C334468 from LifeSpan Bioscience Prices $315.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-SRSF10 / FUSIP1 Antibody (aa133-183) - LS-C286849 from LifeSpan Bioscience Prices $415.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-SRSF10 / FUSIP1 Antibody (aa133-183) - LS-C289035 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-SRSF10 / FUSIP1 Antibody (clone 1A6) - LS-C133661 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1A6

FUSIP1 Antibody - NB110-93598 from Novus Biologicals Prices $99.00, $279.00 Sizes 25 µl, 100 µl Host Rabbit Clonality Polyclonal

FUSIP1 Antibody (1A6) - H00010772-M03 from Novus Biologicals Prices $349.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1A6

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