SRSF10

Gene Symbol SRSF10
Entrez Gene 10772
Alt Symbol FUSIP1, FUSIP2, NSSR, PPP1R149, SFRS13, SFRS13A, SRp38, SRrp40, TASR, TASR1, TASR2
Species Human
Gene Type protein-coding
Description serine/arginine-rich splicing factor 10
Other Description 40 kDa SR-repressor protein|FUS interacting protein (serine-arginine rich) 1|FUS-interacting protein (serine-arginine rich) 2|SR splicing factor 10|TLS-associated SR protein|TLS-associated protein TASR|TLS-associated protein with SR repeats|TLS-associated protein with Ser-Arg repeats|TLS-associated serine-arginine protein 1|TLS-associated serine-arginine protein 2|neural-salient SR protein|protein phosphatase 1, regulatory subunit 149|serine-arginine repressor protein (40 kDa)|splicing factor SRp38|splicing factor, arginine/serine-rich 13|splicing factor, arginine/serine-rich 13A
Swissprots A6NI42 Q96P17 Q5JRI4 Q5JRI2 B4DJP9 Q96G09 Q5JRI3 O75494 A6NIU7 Q5JRH9 O60572 Q5JRI0 A6NFM6
Accessions AAL06098 AAL06099 AAL16666 CAE89263 CAE89624 CAF16752 EAW95103 EAW95104 EAW95105 EAW95106 EAW95107 O75494 AA808243 AF047448 AAC70918 AF067730 AAC26727 AF419331 AAL16665 AF449427 AAL57514 AK001286 BAA91601 AK001479 AK001656 BAG50956 AK054635 AK055311 BAG51498 AK093226 AK125834 BAG54253 AK222994 BAD96714 AK296175 BAG58911 AL133655 AY007101 AY150180 AAN65380 AY150181 AAN65381 BC001107 AAH01107 BC005039 AAH05039 BC010074 AAH10074 BC071575 AAH71575 BX648939 HQ448699 ADQ33177 NM_001191005 NP_001177934 NM_001191006 NP_001177935 NM_001191007 NP_001177936 NM_001191009 NP_001177938 NM_001300936 NP_001287865 NM_001300937 NP_001287866 NM_006625 NP_006616 NM_054016 NP_473357 NR_034035
Function Splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing. Seems to interfere with the U1 snRNP 5'-splice recognition of SNRNP70. Required for splicing repression in M-phase cells and after heat shock. May be involved in regulation of alternative splicing in neurons, with isoform 1 acting as a positive and isoform 3 as a negative regulator. {ECO:0000269|PubMed:11684676, ECO:0000269|PubMed:12419250, ECO:0000269|PubMed:14765198}.
Subcellular Location Nucleus speckle {ECO:0000269|PubMed:11684676}. Cytoplasm {ECO:0000269|PubMed:11684676}.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:11684676, ECO:0000269|PubMed:11891055}.
Top Pathways Spliceosome

FUSIP1 CRISPR/Cas9 KO Plasmid (h) - sc-416960 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FUSIP1 HDR Plasmid (h) - sc-416960-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FUSIP1 Double Nickase Plasmid (h) - sc-416960-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FUSIP1 Double Nickase Plasmid (h2) - sc-416960-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FUSIP1 CRISPR Activation Plasmid (h) - sc-416960-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FUSIP1 CRISPR Activation Plasmid (h2) - sc-416960-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FUSIP1 Lentiviral Activation Particles (h) - sc-416960-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FUSIP1 Lentiviral Activation Particles (h2) - sc-416960-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FUSIP1 RNAi - H00010772-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

FUSIP1 RNAi - H00010772-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU114521 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20598 from Sigma-Aldrich

Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20598 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR13231 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr13231

SRSF10 siRNA (Human) - CRH7340 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SRSF10 - MBS8221097 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SRSF10 (NM_054016.2) - SHH418160 from Creative biogene

Category siRNA
Species Reactivities Human

Human SRSF10 siRNA - orb267842 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SRSF10 shRNA Plasmid (Human) - CHH7340 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SRSF10 miRNA 3'UTR clone - MiUTR3H-07486 from Creative biogene

Species Reactivities Human
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