SRSF10

Gene Symbol	SRSF10
Entrez Gene	10772
Alt Symbol	FUSIP1, FUSIP2, NSSR, PPP1R149, SFRS13, SFRS13A, SRp38, SRrp40, TASR, TASR1, TASR2
Species	Human
Gene Type	protein-coding
Description	serine/arginine-rich splicing factor 10
Other Description	40 kDa SR-repressor protein|FUS interacting protein (serine-arginine rich) 1|FUS-interacting protein (serine-arginine rich) 2|SR splicing factor 10|TLS-associated SR protein|TLS-associated protein TASR|TLS-associated protein with SR repeats|TLS-associated protein with Ser-Arg repeats|TLS-associated serine-arginine protein 1|TLS-associated serine-arginine protein 2|neural-salient SR protein|protein phosphatase 1, regulatory subunit 149|serine-arginine repressor protein (40 kDa)|splicing factor SRp38|splicing factor, arginine/serine-rich 13|splicing factor, arginine/serine-rich 13A
Swissprots	A6NI42 Q96P17 Q5JRI4 Q5JRI2 B4DJP9 Q96G09 Q5JRI3 O75494 A6NIU7 Q5JRH9 O60572 Q5JRI0 A6NFM6
Accessions	AAL06098 AAL06099 AAL16666 CAE89263 CAE89624 CAF16752 EAW95103 EAW95104 EAW95105 EAW95106 EAW95107 O75494 AA808243 AF047448 AAC70918 AF067730 AAC26727 AF419331 AAL16665 AF449427 AAL57514 AK001286 BAA91601 AK001479 AK001656 BAG50956 AK054635 AK055311 BAG51498 AK093226 AK125834 BAG54253 AK222994 BAD96714 AK296175 BAG58911 AL133655 AY007101 AY150180 AAN65380 AY150181 AAN65381 BC001107 AAH01107 BC005039 AAH05039 BC010074 AAH10074 BC071575 AAH71575 BX648939 HQ448699 ADQ33177 NM_001191005 NP_001177934 NM_001191006 NP_001177935 NM_001191007 NP_001177936 NM_001191009 NP_001177938 NM_001300936 NP_001287865 NM_001300937 NP_001287866 NM_006625 NP_006616 NM_054016 NP_473357 NR_034035
Function	Splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing. Seems to interfere with the U1 snRNP 5'-splice recognition of SNRNP70. Required for splicing repression in M-phase cells and after heat shock. May be involved in regulation of alternative splicing in neurons, with isoform 1 acting as a positive and isoform 3 as a negative regulator. {ECO:0000269|PubMed:11684676, ECO:0000269|PubMed:12419250, ECO:0000269|PubMed:14765198}.
Subcellular Location	Nucleus speckle {ECO:0000269|PubMed:11684676}. Cytoplasm {ECO:0000269|PubMed:11684676}.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:11684676, ECO:0000269|PubMed:11891055}.
Top Pathways	Spliceosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FUSIP1 protein fragment - ab161147 from Abcam Category Protein Source Wheat germ Species Human

SRSF10 / FUSIP1 Antibody Blocking Peptide - LS-E5019 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SRSF10 / FUSIP1 Antibody Blocking Peptide - LS-E14895 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SRSF10 / FUSIP1 Antibody Blocking Peptide - LS-E15079 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SRSF10 / FUSIP1 Antibody Blocking Peptide - LS-E15080 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human FUSIP1 Protein - H00010772-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

FUSIP1-Antibody-C-term-Blocking-Peptide - BP17421b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human SRSF10 protein - orb246544 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

FUSIP1 Blocking Peptide - 33R-9019 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FUSIP1 Blocking Peptide - 33R-6494 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FUSIP1 Blocking Peptide - 33R-4659 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SFRS13A / FUSIP1 - H00010772-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SFRS13A / FUSIP1 - H00010772-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

FUSIP1 fusion protein - ag0176 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human FUSIP1, GST-tagged - FUSIP1-13038H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Serine/arginine-rich splicing factor 10(SRSF10) - CSB-YP525638HU CSB-BP525638HU CSB-MP525638HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant Human Serine/arginine-rich splicing factor 10(SRSF10) - CSB-EP525638HU from Cusabio Category Protein Source Yeast Species Human

SFRS13A / FUSIP1 (transcript variant 1) - TP321759 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SRSF10 Peptide, Human - M34GP15177H from Creative Peptides Category Peptide Source Synthetic. Species Human

SRSF10 Recombinant Protein (OPCA02208) - OPCA02208 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Recombinant human Serine/arginine-rich splicing factor 10 - AP71227 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Serine/arginine-rich splicing factor 10, Recombinant Protein - MBS9421102 from MyBioSource Category Protein Prices $280.00, $665.00, $1,080.00, $1,690.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E Coli Species Human

Serine/arginine-rich splicing factor 10 , Recombinant Protein - MBS1119566 from MyBioSource Category Protein Prices $190.00, $460.00, $750.00, $1,015.00, $1,180.00, $1,245.00, $1,245.00, $1,560.00, $2,025.00, $2,025.00 Sizes 50 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 50 µg (Baculovirus), 1 mg (E-Coli), 500 µg (Yeast), 50 µg (Mammalian-Cell), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Recombinant Human Serine/arginine-rich splicing factor 10 (SRSF10) - RPC22909 from Biomatik Category Protein Prices $187.00, $342.00, $1,692.00 Sizes 50 µg, 100 µg, 1 mg Source E.coli Species Human

Recombinant Human SRSF10 Protein (1-183 aa), His-SUMO-tagged - SRSF10-990H from Creative Biomart Category Protein Source E. coli Species Human

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