EDNRA

Gene Symbol	EDNRA
Entrez Gene	1909
Alt Symbol	ET-A, ETA, ETA-R, ETAR, ETRA, hET-AR
Species	Human
Gene Type	protein-coding
Description	endothelin receptor type A
Other Description	G protein-coupled receptor|endothelin receptor subtype A|endothelin-1 receptor|endothelin-1-specific receptor
Swissprots	E7ER36 P25101 Q8TBH2 Q16432 B7Z9G6 B2R723 D3DP03 Q16433 B4E2V6 O43441
Accessions	AAB24923 AAB25212 AAQ87880 BAA01920 EAX05017 EAX05018 EAX05019 EAX05020 EAX05021 P25101 AF014826 AAB94859 AK304451 BAG65268 AK312812 BAG35670 AK315931 BAH14302 AY275462 AAP32294 BC022511 AAH22511 BQ006584 CD723797 D90348 BAA14359 DA183901 DA775295 DA956937 DQ892329 ABM83255 DQ895532 ABM86458 L06622 AAA58447 S45956 AAB23644 S57498 AAB25530 S63938 AAB20278 S67127 AAB20407 S81539 AAB36325 S81542 AAB36326 S81545 AAB36327 X61950 CAA43953 NM_001166055 NP_001159527 NM_001256283 NP_001243212 NM_001957 NP_001948 NR_045958
Function	Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Isoform 1, isoform 3 and isoform 4 are expressed in a variety of tissues, with highest levels in the aorta and cerebellum, followed by lung, atrium and cerebral cortex, lower levels in the placenta, kidney, adrenal gland, duodenum, colon, ventricle and liver but no expression in umbilical vein endothelial cells. Within the placenta, isoform 1, isoform 2, isoform 3 and isoform 4 are expressed in the villi and stem villi vessels. {ECO:0000269|PubMed:8611157, ECO:0000269|PubMed:9284755}.
Top Pathways	Calcium signaling pathway, Vascular smooth muscle contraction, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human EDNRA / Endothelin A Receptor ELISA Kit (Sandwich ELISA) - LS-F6441 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 0.115 ng/ml Range 0.313-20 ng/ml

Endothelin Receptor A (ETRA), Human, ELISA Kit - SEB981Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 0.053ng/mL Range 0.156-10ng/mL

Endothelin-1 receptor (EDNRA), Human, ELISA Kit - CSB-EL007403HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 11.75 pg/ml Range 47 pg/ml-3000 pg/ml

Endothelin-1 receptor (EDNRA), Human, ELISA Kit - E01E0368 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Endothelin-1 receptor, EDNRA, Human, ELISA Kit - E1981h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Endothelin Receptor A, ETRA, Human, ELISA Kit - E-EL-H1758 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Endothelin Receptor A, ETRA, Mouse, ELISA Kit - E-EL-M0459 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Endothelin Receptor A, ETRA, Rabbit, ELISA Kit - E-EL-RB2246 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Endothelin Receptor A, ETRA, Chicken, ELISA Kit - E-EL-Ch0945 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Endothelin Receptor A, ETRA, Porcine, ELISA Kit - E-EL-P1924 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Endothelin Receptor A, ETRA, Monkey, ELISA Kit - E-EL-MK1810 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human ETRA ELISA Kit - HE0071 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine ETRA ELISA Kit - AE0071 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Endothelin Receptor A, ELISA Kit - MBS735752 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Endothelin Receptor A, ELISA Kit - MBS744209 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Endothelin Receptor A, ELISA Kit - MBS723986 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Endothelin Receptor A, ELISA Kit - MBS738866 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Endothelin Receptor A, ELISA Kit - MBS726847 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Endothelin Receptor A, ELISA Kit - MBS737096 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Endothelin Receptor A, ELISA Kit - MBS724315 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Endothelin Receptor A, ELISA Kit - MBS732017 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Endothelin Receptor A, ELISA Kit - MBS737909 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Endothelin Receptor A, ELISA Kit - MBS720360 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Endothelin Receptor A, ELISA Kit - MBS740859 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Endothelin Receptor A, ELISA Kit - MBS738301 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

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