NEO1

Gene Symbol NEO1
Entrez Gene 4756
Alt Symbol IGDCC2, NGN, NTN1R2
Species Human
Gene Type protein-coding
Description neogenin 1
Other Description immunoglobulin superfamily DCC subclass member 2|neogenin|neogenin homolog 1
Swissprots O00340 B7ZKN0 B7ZKM9 Q92859 Q17RX1
Accessions EAW77923 EAW77924 Q92859 AB209412 BAD92649 AL355708 AL359597 AL390182 BC117161 AAI17162 BC143270 AAI43271 BC143271 AAI43272 BC143279 BM564445 DB458571 DB478373 U61262 AAB17263 U72391 AAC51287 XM_005254408 XP_005254465 XM_011521628 XP_011519930 XM_011521629 XP_011519931 XM_011521630 XP_011519932 XM_011521631 XP_011519933 XM_011521632 XP_011519934 XM_011521633 XP_011519935 NM_001172623 NP_001166094 NM_001172624 NP_001166095 NM_002499 NP_002490
Function Multi-functional cell surface receptor regulating cell adhesion in many diverse developmental processes, including neural tube and mammary gland formation, myogenesis and angiogenesis. Receptor for members of the BMP, netrin, and repulsive guidance molecule (RGM) families. Netrin-Neogenin interactions result in a chemoattractive axon guidance response and cell-cell adhesion, the interaction between NEO1/Neogenin and RGMa and RGMb induces a chemorepulsive response. {ECO:0000269|PubMed:21149453}.
Subcellular Location Cell membrane; Single-pass type I membrane protein.
Tissue Specificity Widely expressed and also in cancer cell lines.
Top Pathways Cell adhesion molecules (CAMs)

Human Neogenin peptide - ab27809 from Abcam

Category Peptide

NGN / Neogenin Antibody Blocking Peptide - LS-E5322 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

NGN / Neogenin Antibody Blocking Peptide - LS-E13246 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

NEO1-Antibody-Center-Blocking-Peptide - BP17802c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Neogenin 1 (NEO1) - RPL935Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Neogenin 1 (NEO1) - RPL935Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

Recombinant Human Neogenin(NEO1) ,partial - CSB-YP852917HU CSB-EP852917HU CSB-BP852917HU CSB-MP852917HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

neogenin (1171-1345) - sc-4381 WB from Santa Cruz Biotechnology

Category Protein
Prices $88.00
Sizes 10 µg/0.1 ml
Species Human

Recombinant Human Neogenin Protein, CF - 8607-NE from R&D Systems

Category Protein
Prices $329.00
Sizes 50 µg
Source Human embryonic kidney cell, HEK293-derived Ala34-Met1104, with a C-terminal 6-His tag
Species Human

Neogenin - TP316942 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
Neogenin

Neogenin Recombinant Protein Antigen - NBP1-89653PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

Neogenin Recombinant Protein Antigen - NBP1-89652PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

Neogenin Protein - NBP1-89651PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

NEO1 Peptide, Human - M34GP10301H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Neogenin (NEO1), partial, Recombinant Protein - MBS1471385 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

Recombinant Mouse Neogenin Fc Chimera Protein, CF - 1079-NE from Novus Biologicals

Category Protein
Prices $329.00
Sizes 50 µg
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