NEO1

Gene Symbol NEO1
Entrez Gene 4756
Alt Symbol IGDCC2, NGN, NTN1R2
Species Human
Gene Type protein-coding
Description neogenin 1
Other Description immunoglobulin superfamily DCC subclass member 2|neogenin|neogenin homolog 1
Swissprots O00340 B7ZKN0 B7ZKM9 Q92859 Q17RX1
Accessions EAW77923 EAW77924 Q92859 AB209412 BAD92649 AL355708 AL359597 AL390182 BC117161 AAI17162 BC143270 AAI43271 BC143271 AAI43272 BC143279 BM564445 DB458571 DB478373 U61262 AAB17263 U72391 AAC51287 XM_005254408 XP_005254465 XM_011521628 XP_011519930 XM_011521629 XP_011519931 XM_011521630 XP_011519932 XM_011521631 XP_011519933 XM_011521632 XP_011519934 XM_011521633 XP_011519935 NM_001172623 NP_001166094 NM_001172624 NP_001166095 NM_002499 NP_002490
Function Multi-functional cell surface receptor regulating cell adhesion in many diverse developmental processes, including neural tube and mammary gland formation, myogenesis and angiogenesis. Receptor for members of the BMP, netrin, and repulsive guidance molecule (RGM) families. Netrin-Neogenin interactions result in a chemoattractive axon guidance response and cell-cell adhesion, the interaction between NEO1/Neogenin and RGMa and RGMb induces a chemorepulsive response. {ECO:0000269|PubMed:21149453}.
Subcellular Location Cell membrane; Single-pass type I membrane protein.
Tissue Specificity Widely expressed and also in cancer cell lines.
Top Pathways Cell adhesion molecules (CAMs)

neogenin CRISPR/Cas9 KO Plasmid (h) - sc-401204 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

neogenin HDR Plasmid (h) - sc-401204-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

neogenin Double Nickase Plasmid (h) - sc-401204-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

neogenin Double Nickase Plasmid (h2) - sc-401204-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

neogenin CRISPR Activation Plasmid (h) - sc-401204-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

neogenin CRISPR Activation Plasmid (h2) - sc-401204-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

neogenin Lentiviral Activation Particles (h) - sc-401204-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

neogenin Lentiviral Activation Particles (h2) - sc-401204-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

neogenin siRNA (h) - sc-36028 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

neogenin shRNA Plasmid (h) - sc-36028-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

neogenin shRNA (h) Lentiviral Particles - sc-36028-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Neogenin RNAi - H00004756-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU061751 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15210 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15210 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

NEO1 siRNA (Human) - CRH3157 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Neo1 (NM_002499.3) - SHH351376 from Creative biogene

Category siRNA
Species Reactivities Human

Human NEO1 siRNA - orb263659 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NEO1 shRNA Plasmid (Human) - CHH3157 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NEO1 miRNA 3'UTR clone - MiUTR4H-TG05959 from Creative biogene

Species Reactivities Human
Search more