IRF4

Gene Symbol	IRF4
Entrez Gene	3662
Alt Symbol	LSIRF, MUM1, NF-EM5, SHEP8
Species	Human
Gene Type	protein-coding
Description	interferon regulatory factor 4
Other Description	lymphocyte-specific interferon regulatory factor|multiple myeloma oncogene 1
Swissprots	Q15306 Q99660 Q5VUI7
Accessions	EAW55056 EAW55057 EAW55058 EAW55059 EAW55060 Q15306 AK130762 AK310149 AW197089 BC015752 AAH15752 BG230623 BM551611 CR977713 D78261 BAA11335 DQ893472 ABM84398 DQ896302 ABM87301 U52682 AAC50779 U63738 AAB37258 XM_006715090 XP_006715153 NM_001195286 NP_001182215 NM_002460 NP_002451 NR_046000 NR_036585
Function	Transcriptional activator. Binds to the interferon- stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity). {ECO:0000250|UniProtKB:Q64287}.
Subcellular Location	Nucleus.
Tissue Specificity	Lymphoid cells.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MUM1 full length protein - ab132104 from Abcam Category Protein Source Wheat germ Species Human

Human MUM1 protein fragment - ab83638 from Abcam Category Protein Source E. coli Species Human

IRF4 Antibody Blocking Peptide - LS-E1826 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IRF4 Antibody Blocking Peptide - LS-E27831 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IRF4 Antibody Blocking Peptide - LS-E11478 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IRF4 Antibody Blocking Peptide - LS-E13700 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IRF4 Antibody Blocking Peptide - LS-E13701 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IRF4 Antibody Blocking Peptide - LS-E31117 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

MUM1 Antibody Blocking Peptide - LS-E5254 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human IRF4 Protein - H00003662-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human IRF4 Protein - H00003662-P01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

IRF4 Blocking Peptide - NBP1-76574PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

IRF4-Antibody-Center-Blocking-peptide - BP12637c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

IRF4 Protein (OPPA01405) - OPPA01405 from Aviva Systems Biology Category Protein Prices $315.00 Sizes 2 µg Source E. Coli

Human IRF4 MUM-1 protein - orb81174 from Biorbyt Category Protein Prices $323.00, $595.00, $1,139.00 Sizes 100 μg, 500 μg, 1 mg Source E.coli

IRF4 protein - orb197701 from Biorbyt Category Protein Prices $255.00, $391.00, $519.00 Sizes 10 μg, 50 μg, 100 μg Species Human

IRF4 Blocking Peptide - abx062142 from Abbexa Category Peptide Species Human

MUM1 Peptide - AC21-2641-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

IRF4 - H00003662-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Source in vitro transl. Species Human

IRF4 - H00003662-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Source in vitro transl. Species Human

IRF4 - H00003662-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

IRF4 - H00003662-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

IRF4 control peptide - AP26140CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Recombinant Human IRF4 - 230-00605-10 from RayBiotech Category Protein Prices $110.00 Sizes 10 µg Source Escherichia coli (E.coli) Species Human

Recombinant Human IRF4 - 230-00605-100 from RayBiotech Category Protein Prices $336.00 Sizes 100 µg Source Escherichia coli (E.coli) Species Human

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