IRF4

Gene Symbol IRF4
Entrez Gene 3662
Alt Symbol LSIRF, MUM1, NF-EM5, SHEP8
Species Human
Gene Type protein-coding
Description interferon regulatory factor 4
Other Description lymphocyte-specific interferon regulatory factor|multiple myeloma oncogene 1
Swissprots Q15306 Q99660 Q5VUI7
Accessions EAW55056 EAW55057 EAW55058 EAW55059 EAW55060 Q15306 AK130762 AK310149 AW197089 BC015752 AAH15752 BG230623 BM551611 CR977713 D78261 BAA11335 DQ893472 ABM84398 DQ896302 ABM87301 U52682 AAC50779 U63738 AAB37258 XM_006715090 XP_006715153 NM_001195286 NP_001182215 NM_002460 NP_002451 NR_046000 NR_036585
Function Transcriptional activator. Binds to the interferon- stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity). {ECO:0000250|UniProtKB:Q64287}.
Subcellular Location Nucleus.
Tissue Specificity Lymphoid cells.

IRF-4 CRISPR/Cas9 KO Plasmid (h) - sc-400288 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRF-4 HDR Plasmid (h) - sc-400288-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRF-4 Double Nickase Plasmid (h) - sc-400288-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRF-4 Double Nickase Plasmid (h2) - sc-400288-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRF-4 CRISPR Activation Plasmid (h) - sc-400288-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRF-4 CRISPR Activation Plasmid (h2) - sc-400288-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRF-4 Lentiviral Activation Particles (h) - sc-400288-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRF-4 Lentiviral Activation Particles (h2) - sc-400288-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRF-4 siRNA (h) - sc-35712 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IRF-4 shRNA Plasmid (h) - sc-35712-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IRF-4 shRNA (h) Lentiviral Particles - sc-35712-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IRF-4 siRNA (h2) - sc-270125 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IRF-4 shRNA Plasmid (h2) - sc-270125-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IRF-4 shRNA (h2) Lentiviral Particles - sc-270125-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IRF4 RNAi - H00003662-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human
Western Blot: IRF4 RNAi [H00003662-R01V] - Western blot aAcell line, cotransfected with IRF4 Validated Chimera RNAi or non-transfected control. Blot probed with H00003662-M05. GAPDH (36.1 kDa) used as loading control.

MISSION® esiRNA - EHU062171 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10766 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10766 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

IRF4 siRNA (Human) - CRH2455 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IRF4 RNAi - H00003662-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

IRF4 - MBS827482 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IRF4 shRNA Plasmid (Human) - CHH2455 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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