TFE3

Gene Symbol TFE3
Entrez Gene 7030
Alt Symbol RCCP2, RCCX1, TFEA, bHLHe33
Species Human
Gene Type protein-coding
Description transcription factor binding to IGHM enhancer 3
Other Description class E basic helix-loop-helix protein 33|transcription factor E family, member A|transcription factor E3|transcription factor for IgH enhancer|transcription factor for immunoglobulin heavy-chain enhancer 3
Swissprots Q5JU74 Q92758 Q92757 P19532 A8MZL6 Q99964
Accessions CAA65800 CAA68061 EAW50711 EAW50712 EAW50713 EAW50714 P19532 AK295497 BAG58417 AK310095 AK313540 BAG36317 AL161985 CAI46207 BC001532 BC026027 AAH26027 BM904206 EU446500 ABZ92029 EU831602 ACE87202 EU831689 ACE86523 HY157114 X51330 CAA35714 X96717 CAA65478 XM_006724549 XP_006724612 XM_011543952 XP_011542254 NM_001282142 NP_001269071 NM_006521 NP_006512
Function Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
Subcellular Location Nucleus.
Tissue Specificity Ubiquitous in fetal and adult tissues.
Top Pathways Transcriptional misregulation in cancer

TFE3 Antibody - 14779 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using TFE3 Antibody.

TFE3 (H-300) - sc-28733 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TFE3 (H-300): sc-28733. Western blot analysis of TFE3 expression in non-transfected: sc-117752 (A) and human TFE3 transfected: sc-178032 (B) 293T whole cell lysates.

TFE3 (N-15) - sc-5956 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TFE3 (P-16) - sc-5958 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TFE3 (P-16): sc-5958. Western blot analysis of TFE3 expression in A549 whole cell lysate.

Anti-TFE3 antibody - ab196681 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TFE3 antibody (ab196681) at 1/500 dilutionLane 1 : K562 cell extractLane 2 : A549 cell extractLane 3 : A549 cell extract with immunizing peptide

Anti-TFE3 antibody - ab86127 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TFE3 antibody (ab86127) at 1 µg/mlLane 1 : A549 (Human lung adenocarcinoma epithelial cell line) Whole Cell LysateLane 2 : A549 (Human lung adenocarcinoma epithelial cell line) Whole Cell Lysate with Immunizing peptide at 1 µg/mlLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-TFE3 antibody - ab36642 from Abcam

Prices $376.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
Anti-TFE3 antibody (ab36642) at 1/2000 dilution + E. coli-derived TFE3 fusion protein at 2.5 µgSecondaryGoat anti-IgY-HRP at 1/1000 dilution

Anti-TFE3 antibody - ab97667 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-TFE3 antibody (ab97667) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

Anti-TFE3 antibody - ab93808 from Abcam

Prices $376.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TFE3 antibody (ab93808) at 0.04 µg/mlLane 1 : HeLa whole lysate at 50 µgLane 2 : HeLa whole lysate at 15 µgLane 3 : HeLa whole lysate at 5 µgLane 4 : 293T cell lysate at 50 µgdeveloped using the ECL technique

Anti-TFE3 antibody - ab90681 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-TFE3 antibody (ab90681) at 1 µg/ml (in 5% skim milk / PBS buffer) + NCI-H226 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-TFE3 antibody [EPR11591] - ab179804 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11591
Immunofluorescent analysis of HeLa cells labeling TFE3 with ab179804 at 1/50 dilution (red). DAPI nuclear staining (blue).

Anti-TFE3 antibody - N-terminal - ab173928 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-TFE3 antibody - N-terminal (ab173928) at 1/100 dilution + Mouse lung lysate at 35 µg

Anti-TFE3 Antibody (aa2-15) - LS-C55580 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-TFE3 Antibody (aa318-476) - LS-C189270 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-TFE3 Antibody (aa489-516, AP) - LS-C271324 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TFE3 Antibody (aa489-516, APC) - LS-C271325 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TFE3 Antibody (aa489-516, Biotin) - LS-C271326 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TFE3 Antibody (aa489-516, FITC) - LS-C271327 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TFE3 Antibody (aa489-516, Azide-free, HRP) - LS-C271328 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TFE3 Antibody (aa489-516, PE) - LS-C271329 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TFE3 Antibody (aa324-373) - LS-C109793 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TFE3 antibody LS-C109793 Western blot of MCF7 cell lysate.

Anti-TFE3 Antibody (aa1-30, AP) - LS-C271330 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TFE3 Antibody (aa503-552) - LS-C109794 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TFE3 antibody LS-C109794 Western blot of NCI-H226 cell lysate.

Anti-TFE3 Antibody (aa303-307) - LS-C205099 from LifeSpan Bioscience

Prices $265.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Western blot of extracts from 293 cells using TFE3 antibody.

Anti-TFE3 Antibody (aa1-30, APC) - LS-C271331 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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