TFE3

Gene Symbol TFE3
Entrez Gene 7030
Alt Symbol RCCP2, RCCX1, TFEA, bHLHe33
Species Human
Gene Type protein-coding
Description transcription factor binding to IGHM enhancer 3
Other Description class E basic helix-loop-helix protein 33|transcription factor E family, member A|transcription factor E3|transcription factor for IgH enhancer|transcription factor for immunoglobulin heavy-chain enhancer 3
Swissprots Q5JU74 Q92758 Q92757 P19532 A8MZL6 Q99964
Accessions CAA65800 CAA68061 EAW50711 EAW50712 EAW50713 EAW50714 P19532 AK295497 BAG58417 AK310095 AK313540 BAG36317 AL161985 CAI46207 BC001532 BC026027 AAH26027 BM904206 EU446500 ABZ92029 EU831602 ACE87202 EU831689 ACE86523 HY157114 X51330 CAA35714 X96717 CAA65478 XM_006724549 XP_006724612 XM_011543952 XP_011542254 NM_001282142 NP_001269071 NM_006521 NP_006512
Function Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
Subcellular Location Nucleus.
Tissue Specificity Ubiquitous in fetal and adult tissues.
Top Pathways Transcriptional misregulation in cancer

TFE3 CRISPR/Cas9 KO Plasmid (h) - sc-401179 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFE3 HDR Plasmid (h) - sc-401179-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFE3 Double Nickase Plasmid (h) - sc-401179-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFE3 Double Nickase Plasmid (h2) - sc-401179-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFE3 CRISPR Activation Plasmid (h) - sc-401179-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFE3 CRISPR Activation Plasmid (h2) - sc-401179-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFE3 Lentiviral Activation Particles (h) - sc-401179-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFE3 Lentiviral Activation Particles (h2) - sc-401179-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFE3 siRNA (h) - sc-38507 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TFE3 shRNA Plasmid (h) - sc-38507-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TFE3 shRNA (h) Lentiviral Particles - sc-38507-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Transcription factor E3 RNAi - H00007030-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU157921 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2348 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2348 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09606 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09606

TFE3 siRNA (Human) - CRH4804 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TFE3 - MBS8203764 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TFE3 (NM_006521.4) - SHH426192 from Creative biogene

Category siRNA
Species Reactivities Human

Human TFE3 siRNA - orb265306 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TFE3 shRNA Plasmid (Human) - CHH4804 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TFE3 miRNA 3'UTR clone - MiUTR3H-03028 from Creative biogene

Species Reactivities Human
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