TFE3

Gene Symbol	TFE3
Entrez Gene	7030
Alt Symbol	RCCP2, RCCX1, TFEA, bHLHe33
Species	Human
Gene Type	protein-coding
Description	transcription factor binding to IGHM enhancer 3
Other Description	class E basic helix-loop-helix protein 33|transcription factor E family, member A|transcription factor E3|transcription factor for IgH enhancer|transcription factor for immunoglobulin heavy-chain enhancer 3
Swissprots	Q5JU74 Q92758 Q92757 P19532 A8MZL6 Q99964
Accessions	CAA65800 CAA68061 EAW50711 EAW50712 EAW50713 EAW50714 P19532 AK295497 BAG58417 AK310095 AK313540 BAG36317 AL161985 CAI46207 BC001532 BC026027 AAH26027 BM904206 EU446500 ABZ92029 EU831602 ACE87202 EU831689 ACE86523 HY157114 X51330 CAA35714 X96717 CAA65478 XM_006724549 XP_006724612 XM_011543952 XP_011542254 NM_001282142 NP_001269071 NM_006521 NP_006512
Function	Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
Subcellular Location	Nucleus.
Tissue Specificity	Ubiquitous in fetal and adult tissues.
Top Pathways	Transcriptional misregulation in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TFE3 protein fragment - ab152741 from Abcam Category Protein Source Wheat germ Species Human

TFE3 peptide - ab109924 from Abcam Category Peptide

TFE3 Antibody Blocking Peptide - LS-E5776 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TFE3 Antibody Blocking Peptide - LS-E5777 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TFE3 Antibody Blocking Peptide - LS-E25349 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TFE3 Antibody Blocking Peptide - LS-E11815 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Transcription factor E3 Recombinant Protein - H00007030-P01 from Novus Biologicals Category Protein Species Human

Recombinant Human Transcription factor E3 Protein - H00007030-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TFE3-Antibody-C-term-Blocking-Peptide - BP18317b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TFE3-Antibody-N-term-Blocking-Peptide - BP18316a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TFE3 blocking peptide - GTX89882-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Bovine

TFE3 Blocking Peptide - abx063343 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Dog, Pig

TFE3 Peptide - AC21-0177-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

TFE3 - H00007030-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

TFE3 - H00007030-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

TFE3 - H00007030-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TFE3 - H00007030-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TFE3 Peptide - 46-482P from ProSci Category Peptide Species Human

TFE3 fusion protein - Ag5863 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

TFE3 fusion protein - Ag6320 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human TFE3 - TFE3-218H from Creative Biomart Category Protein Source Recombinant Human TFE-3 protein encloding 318-476 amino acids expressed in E. coli.

Recombinant Human TFE3, GST-tagged - TFE3-3201H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human TFE3 - TFE3-452H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Transcription Factor Binding To IGHM Enhancer 3 (TFE3) - RPJ718Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

TFE3 Blocking Peptide - CBP2149 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Dog, Pig

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