NCL

Gene Symbol NCL
Entrez Gene 4691
Alt Symbol C23
Species Human
Gene Type protein-coding
Description nucleolin
Other Description -
Swissprots Q9UCF0 Q53SK1 Q9UDG1 Q8NB06 P19338
Accessions AAA59954 AAY24247 CCQ43318 EAW70960 EAW70961 EAW70962 EAW70963 P19338 AK000221 AK000250 AK001314 BAG50892 AK091742 BAC03738 AK095897 BAG53161 AK122805 AK127608 BAC87055 AK128584 AY320411 BC002343 AAH02343 BC006494 AAH06494 BC006516 AAH06516 BM761058 BQ001029 NM_005381 NP_005372
Function Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. {ECO:0000269|PubMed:10393184}.
Subcellular Location Nucleus, nucleolus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Top Pathways Pathogenic Escherichia coli infection

C23 CRISPR/Cas9 KO Plasmid (h) - sc-400191 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C23 HDR Plasmid (h) - sc-400191-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C23 Double Nickase Plasmid (h) - sc-400191-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C23 Double Nickase Plasmid (h2) - sc-400191-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C23 CRISPR Activation Plasmid (h) - sc-400191-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C23 CRISPR Activation Plasmid (h2) - sc-400191-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C23 Lentiviral Activation Particles (h) - sc-400191-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C23 Lentiviral Activation Particles (h2) - sc-400191-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C23 siRNA (h) - sc-29230 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C23 shRNA Plasmid (h) - sc-29230-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C23 shRNA (h) Lentiviral Particles - sc-29230-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nucleolin RNAi - H00004691-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU080431 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15025 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15025 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03857 from Sigma-Aldrich

Category miRNA

NCL siRNA (Human) - CRH3106 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NCL (NM_005381.2) - SHH350048 from Creative biogene

Category siRNA
Species Reactivities Human

NCL shRNA Plasmid (Human) - CHH3106 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NCL miRNA 3'UTR clone - MiUTR1H-06683 from Creative biogene

Species Reactivities Human
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