RRAS2

Gene Symbol RRAS2
Entrez Gene 22800
Alt Symbol TC21
Species Human
Gene Type protein-coding
Description related RAS viral (r-ras) oncogene homolog 2
Other Description ras-like protein TC21|ras-related protein R-Ras2|teratocarcinoma oncogene
Swissprots P62070 B7Z7H6 P17082 B7Z6C4 B7Z5Z2 B2R9Z3
Accessions EAW68486 EAW68487 P62070 AA873016 AF493924 AAM12638 AK299606 BAH13078 AK300103 BAH13210 AK302033 BAH13612 AK309550 AK309683 AK313976 BAG36690 BC013106 AAH13106 BG428983 BP206021 BP206589 BQ020351 BQ023701 BX324335 CB961515 DC368033 M31468 AAA36545 NM_001102669 NP_001096139 NM_001177314 NP_001170785 NM_001177315 NP_001170786 NM_012250 NP_036382
Function It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion.
Subcellular Location Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS).
Tissue Specificity Ubiquitously present in all tissues examined, with the highest levels in heart, placenta, and skeletal muscle. Moderate levels in lung and liver; low levels in brain, kidney, and pancreas. {ECO:0000269|PubMed:8052619}.
Top Pathways Tight junction, MAPK signaling pathway, HTLV-I infection, cAMP signaling pathway, Proteoglycans in cancer

TC 21 CRISPR/Cas9 KO Plasmid (h) - sc-405208 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TC 21 HDR Plasmid (h) - sc-405208-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TC 21 Double Nickase Plasmid (h) - sc-405208-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TC 21 Double Nickase Plasmid (h2) - sc-405208-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TC 21 CRISPR Activation Plasmid (h) - sc-405208-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TC 21 CRISPR Activation Plasmid (h2) - sc-405208-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TC 21 Lentiviral Activation Particles (h) - sc-405208-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TC 21 Lentiviral Activation Particles (h2) - sc-405208-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TC 21 siRNA (h) - sc-41861 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TC 21 shRNA Plasmid (h) - sc-41861-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TC 21 shRNA (h) Lentiviral Particles - sc-41861-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TC21/R-Ras2 RNAi - H00022800-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

TC21/R-Ras2 RNAi - H00022800-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU108181 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18681 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18681 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04521 from Sigma-Aldrich

Category miRNA

RRAS2 siRNA (Human) - CRH7779 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RRAS2 - MBS8237181 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TC 21 CRISPR/Cas9 KO Plasmid (h2) - sc-405208-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TC 21 HDR Plasmid (h2) - sc-405208-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human RRAS2 (NM_012250.5) - SHH399904 from Creative biogene

Category siRNA
Species Reactivities Human

Human RRAS2 siRNA - orb268281 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RRAS2 shRNA Plasmid (Human) - CHH7779 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

RRAS2 miRNA 3'UTR clone - MiUTR3H-03135 from Creative biogene

Species Reactivities Human
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