RRAS2

Gene Symbol	RRAS2
Entrez Gene	22800
Alt Symbol	TC21
Species	Human
Gene Type	protein-coding
Description	related RAS viral (r-ras) oncogene homolog 2
Other Description	ras-like protein TC21|ras-related protein R-Ras2|teratocarcinoma oncogene
Swissprots	P62070 B7Z7H6 P17082 B7Z6C4 B7Z5Z2 B2R9Z3
Accessions	EAW68486 EAW68487 P62070 AA873016 AF493924 AAM12638 AK299606 BAH13078 AK300103 BAH13210 AK302033 BAH13612 AK309550 AK309683 AK313976 BAG36690 BC013106 AAH13106 BG428983 BP206021 BP206589 BQ020351 BQ023701 BX324335 CB961515 DC368033 M31468 AAA36545 NM_001102669 NP_001096139 NM_001177314 NP_001170785 NM_001177315 NP_001170786 NM_012250 NP_036382
Function	It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion.
Subcellular Location	Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS).
Tissue Specificity	Ubiquitously present in all tissues examined, with the highest levels in heart, placenta, and skeletal muscle. Moderate levels in lung and liver; low levels in brain, kidney, and pancreas. {ECO:0000269|PubMed:8052619}.
Top Pathways	Tight junction, MAPK signaling pathway, HTLV-I infection, cAMP signaling pathway, Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RRAS2 full length protein - ab87714 from Abcam Category Protein Source E. coli Species Human

Human RRAS2 full length protein - ab90741 from Abcam Category Protein Source E. coli Species Human

TC21 / RRAS2 Antibody Blocking Peptide - LS-E31406 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TC21/R-Ras2 Recombinant Protein - H00022800-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human TC21/R-Ras2 Protein - NBP1-30244 from Novus Biologicals Category Protein Prices $229.00 Sizes 100 µg Species Human

RRAS2 Protein (OPPA02176) - OPPA02176 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 10 µg

TC21/RRas2 His tag (Q72L) protein - orb84946 from Biorbyt Category Protein Prices $425.00 Sizes 50 μg Source NM_012250 Species Human

Human Related RAS Viral (r-ras) Oncogene Homolog 2 protein - orb81327 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 10 μg, 50 μg Source E.coli

RRAS protein (His tag) - 80R-1299 from Fitzgerald Category Protein Prices $395.00 Sizes 50 µg Source E.coli

RRAS2 protein (His tag) - 80R-1201 from Fitzgerald Category Protein Prices $180.00 Sizes 100 µg Source E.coli

RRAS2 Blocking Peptide - abx063743 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Monkey

RRAS2 / TC21 (1-201, His-tag) - AR09279PU-L from Acris Antibodies Category Protein Prices $585.00 Sizes 500 µg Source E. coli Species Human

RRAS2 / TC21 (1-201, His-tag) - AR09279PU-N from Acris Antibodies Category Protein Prices $270.00 Sizes 100 µg Source E. coli Species Human

RRAS2 / TC21 - H00022800-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

RRAS2 / TC21 - H00022800-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

RRAS2, 1- 201 aa, Human, His-tagged, Recombinant, E.coli - 01-RRAS2 from ARP American Research Products Category Protein Prices $139.00, $299.00, $639.00 Sizes 20 µg, 100 µg, 500 µg Source E.coli Species Human

RRAS2 Peptide - 7249P from ProSci Category Peptide Species Human

RRAS2 fusion protein - Ag3226 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human RRAS2 Protein - BP002265-PRO-728 from Syd Labs Category Protein Prices $160.00, $1,800.00 Sizes 50 µg, 1 mg Source E. coli-derived. Species Human

RRAS2, 1- 201 aa, Recombinant Protein - GWB-P1642D from Genway Biotech Category Protein Prices $210.00, $630.00 Sizes 100 μg, 500 μg Source E.coli Species Human

Recombinant Human Related RAS Viral (r-ras) Oncogene Homolog 2 - GWB-1DD700 from Genway Biotech Category Protein Prices $75.00, $165.00, $1,195.00 Sizes 10 μg, 50 μg, 1000 μg Species Human

Recombinant Human RRAS2, His-tagged - RRAS2-29988TH from Creative Biomart Category Protein Source E. coli

Recombinant Human RRAS2 - RRAS2-30472TH from Creative Biomart Category Protein Source E. coli

Recombinant Human RRAS2, GST-tagged - RRAS2-2443H from Creative Biomart Category Protein Source E.coli Species Human

RRAS 1-215 aa - CMB-367 from Reagent Proteins Category Protein Prices $539.00, $1,099.00 Sizes 50.00 µg, 250.00 µg Source E.coli Species Human

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