DRD3

Gene Symbol DRD3
Entrez Gene 1814
Alt Symbol D3DR, ETM1, FET1
Species Human
Gene Type protein-coding
Description dopamine receptor D3
Other Description D(3) dopamine receptor|essential tremor 1
Swissprots Q4VBM8 A1A4V5 P35462
Accessions AAB08750 CAA01483 CAB70095 EAW79605 EAW79606 EAW79607 EAW79608 EAW79609 EAW79610 EAW79611 EAW79612 P35462 AK292309 BAF84998 AY228454 AY228455 AY228456 AY228457 AY228458 AY228459 BC095510 AAH95510 BC128122 AAI28123 BC128123 AAI28124 KJ534829 AHW56469 KJ535032 AHW56671 L20469 AAA03543 U32499 AAA73929 XM_011512510 XP_011510812 XM_011512511 XP_011510813 XM_011512512 XP_011510814 NM_000796 NP_000787 NM_001282563 NP_001269492 NM_001290809 NP_001277738 NM_033663 NP_387512 NM_033658 NM_033659 NM_033660
Function Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation. {ECO:0000269|PubMed:19520868}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:19520868}; Multi-pass membrane protein {ECO:0000269|PubMed:19520868}. Note=Both membrane-bound and scattered in the cytoplasm during basal conditions. Receptor stimulation results in the rapid internalization and sequestration of the receptors at the perinuclear area (5 and 15 minutes), followed by the dispersal of the receptors to the membrane (30 minutes). DRD3 and GRK4 co- localize in lipid rafts of renal proximal tubule cells.
Tissue Specificity Brain.
Top Pathways Dopaminergic synapse, Neuroactive ligand-receptor interaction

D3DR CRISPR/Cas9 KO Plasmid (h) - sc-402172 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

D3DR HDR Plasmid (h) - sc-402172-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

D3DR Double Nickase Plasmid (h) - sc-402172-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

D3DR Double Nickase Plasmid (h2) - sc-402172-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

D3DR CRISPR Activation Plasmid (h) - sc-402172-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

D3DR CRISPR Activation Plasmid (h2) - sc-402172-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

D3DR Lentiviral Activation Particles (h) - sc-402172-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

D3DR Lentiviral Activation Particles (h2) - sc-402172-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

D3DR siRNA (h) - sc-35163 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

D3DR shRNA Plasmid (h) - sc-35163-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

D3DR shRNA (h) Lentiviral Particles - sc-35163-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dopamine D3 R/DRD3 RNAi - H00001814-R08 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Dopamine D3 R/DRD3 RNAi - H00001814-R09 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Dopamine D3 R/DRD3 RNAi - H00001814-R07 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Dopamine D3 R/DRD3 RNAi - H00001814-R10 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU123071 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1816 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1816 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

Dopamine D3 R/DRD3 RNAi - H00001814-R06 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human DRD3 (NM_000796.3) - SHH281033 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human DRD3(NM_000796.3) - SHH015707 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human DRD3(NM_033663.3) - SHH015761 from Creative biogene

Category siRNA
Species Reactivities Human

DRD3 miRNA 3'UTR clone - MiUTR1H-02995 from Creative biogene

Species Reactivities Human
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