DRD3

Gene Symbol DRD3
Entrez Gene 1814
Alt Symbol D3DR, ETM1, FET1
Species Human
Gene Type protein-coding
Description dopamine receptor D3
Other Description D(3) dopamine receptor|essential tremor 1
Swissprots Q4VBM8 A1A4V5 P35462
Accessions AAB08750 CAA01483 CAB70095 EAW79605 EAW79606 EAW79607 EAW79608 EAW79609 EAW79610 EAW79611 EAW79612 P35462 AK292309 BAF84998 AY228454 AY228455 AY228456 AY228457 AY228458 AY228459 BC095510 AAH95510 BC128122 AAI28123 BC128123 AAI28124 KJ534829 AHW56469 KJ535032 AHW56671 L20469 AAA03543 U32499 AAA73929 XM_011512510 XP_011510812 XM_011512511 XP_011510813 XM_011512512 XP_011510814 NM_000796 NP_000787 NM_001282563 NP_001269492 NM_001290809 NP_001277738 NM_033663 NP_387512 NM_033658 NM_033659 NM_033660
Function Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation. {ECO:0000269|PubMed:19520868}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:19520868}; Multi-pass membrane protein {ECO:0000269|PubMed:19520868}. Note=Both membrane-bound and scattered in the cytoplasm during basal conditions. Receptor stimulation results in the rapid internalization and sequestration of the receptors at the perinuclear area (5 and 15 minutes), followed by the dispersal of the receptors to the membrane (30 minutes). DRD3 and GRK4 co- localize in lipid rafts of renal proximal tubule cells.
Tissue Specificity Brain.
Top Pathways Dopaminergic synapse, Neuroactive ligand-receptor interaction

D3DR (9F4) - sc-136170 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

D3DR (H-50) - sc-9114 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
D3DR (H-50): sc-9114. Western blot analysis of D3DR expression in mouse brain extract.

D3DR (R-15) - sc-33922 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

D3DR (S-16) - sc-9185 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

D3DR (S-19) - sc-33921 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

D3NF (C-16) - sc-9184 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Dopamine Receptor D3 antibody - ab42114 from Abcam

Prices $415.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Dopamine Receptor D3 antibody (ab42114) at 1/750 dilution + PC-D3R sample

Anti-Dopamine Receptor D3 antibody - ab40655 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab40655 stained PC12 cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab40655 at 5µg/ml overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-Dopamine Receptor D3 antibody - ab115675 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab115675, at 20µg/ml, staining Dopamine Receptor D3 in Formalin-fixed, Paraffin-embedded Human Brain cortex tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Dopamine Receptor D3 antibody [EPR10148] - ab155098 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10148
All lanes : Anti-Dopamine Receptor D3 antibody [EPR10148] (ab155098) at 1/1000 dilutionLane 1 : SH-SY5Y lysateLane 2 : Human fetal brain lysateLane 3 : Mouse brain lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-DRD3 / Dopamine Receptor D3 Antibody (aa2-10) - LS-C22899 from LifeSpan Bioscience

Prices $1,035.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DRD3 / Dopamine Receptor D3 Antibody (aa2-10) - LS-C22898 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DRD3 / Dopamine Receptor D3 Antibody (3rd Cytoplasmic Domain) - LS-C22928 from LifeSpan Bioscience

Prices $530.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-DRD3 / Dopamine Receptor D3 Antibody (3rd Cytoplasmic Domain) - LS-C22930 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-DRD3 / Dopamine Receptor D3 Antibody (aa252-284) - LS-C22900 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-DRD3 / Dopamine Receptor D3 Antibody (3rd Cytoplasmic Domain) - LS-C22931 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-DRD3 / Dopamine Receptor D3 Antibody - LS-C64976 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DRD3 / Dopamine Receptor D3 Antibody - LS-C64978 from LifeSpan Bioscience

Prices $435.00
Sizes 5 ml
Host Rabbit
Clonality Polyclonal

Anti-DRD3 / Dopamine Receptor D3 Antibody - LS-C86064 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-DRD3 / Dopamine Receptor D3 Antibody - LS-C64977 from LifeSpan Bioscience

Prices $635.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-DRD3 / Dopamine Receptor D3 Antibody - LS-C86999 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-DRD3 / Dopamine Receptor D3 Antibody - LS-C341195 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DRD3 / Dopamine Receptor D3 Antibody (aa352-367) - LS-C312740 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
DRD3 / Dopamine Receptor D3 antibody. IHC(P): Rat Brain Tissue.

Anti-DRD3 / Dopamine Receptor D3 Antibody (aa270-319) - LS-C146243 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
DRD3 / Dopamine Receptor D3 antibody LS-C146243 Western blot of HepG2 Cell lysate. Antibody concentration 1 ug/ml.

Anti-DRD3 / Dopamine Receptor D3 Antibody - LS-C331534 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of Mouse brain tissue, using DRD3 antibody.
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