ACPP

Gene Symbol	ACPP
Entrez Gene	55
Alt Symbol	5'-NT, ACP-3, ACP3
Species	Human
Gene Type	protein-coding
Description	acid phosphatase, prostate
Other Description	5'-nucleotidase|TMPase|ecto-5'-nucleotidase|prostatic acid phosphatase|prostatic acid phosphotase|thiamine monophosphatase
Swissprots	D3DNC6 Q96QM0 Q96QK9 Q96KY0 Q5FBY0 P15309
Accessions	AAA60021 AAB60640 CAA50514 CAA52913 EAW79201 EAW79202 EAW79203 EAW79204 EAW79205 P15309 AA578274 AB102888 BAD89417 AK300540 BAG62248 AW136372 BC007460 AAH07460 BC008493 AAH08493 BC016344 AAH16344 BC017877 AAH17877 BQ100881 DC383453 DQ893148 ABM84074 DQ896443 ABM87442 M24902 AAA60022 M34840 AAA69694 X52174 CAA36422 X53605 CAA37673 XM_011512946 XP_011511248 XM_011512947 XP_011511249 NM_001099 NP_001090 NM_001134194 NP_001127666 NM_001292037 NP_001278966
Function	A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma.
Subcellular Location	Isoform 1: Secreted.
Tissue Specificity	Highly expressed in the prostate, restricted to glandular and ductal epithelial cells. Also expressed in bladder, kidney, pancreas, lung, cervix, testis and ovary. Weak expression in a subset of pancreatic islet cells, squamous epithelia, the pilosebaceous unit, colonic neuroendocrine cells and skin adnexal structures. Isoform 2 also expressed in the sarcolemma of skeletal muscle. Levels of this cellular isoform decreased in prostate cancer. {ECO:0000269|PubMed:17638863, ECO:0000269|PubMed:21487525}.
Top Pathways	Riboflavin metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Prostatic Acid Phosphatase full length protein - ab152091 from Abcam Category Protein Source HEK 293 cells Species Human

Human Prostatic Acid Phosphatase full length protein - ab202231 from Abcam Category Protein Source E. coli Species Human

Human Prostatic Acid Phosphatase full length protein - ab96164 from Abcam Category Protein Source Native Species Human

Human Prostatic Acid Phosphatase protein fragment - ab134844 from Abcam Category Protein Source E. coli Species Human

ACPP / PAP Antibody Blocking Peptide - LS-E27682 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ACPP / PAP Antibody Blocking Peptide - LS-E9082 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ACPP / PAP Antibody Blocking Peptide - LS-E27071 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ACPP / PAP Antibody Blocking Peptide - LS-E15428 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Prostatic Acid Phosphatase/ACPP Protein - H00000055-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Prostatic Acid Phosphatase/ACPP Partial Recombinant Protein - H00000055-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Prostatic Acid Phosphatase/ACPP Protein - NBP1-42806 from Novus Biologicals Category Protein Prices $699.00 Sizes 1 mg

Prostatic Acid Phosphatase/ACPP Peptide - P2601 from Novus Biologicals Category Peptide Species Human

Prostatic Acid Phosphatase/ACPP Protein - P5207 from Novus Biologicals Category Protein Prices $219.00 Sizes 1 g Species Plant

Mouse-Acpp-Antibody-C-term-Blocking-Peptide - BP19633b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg Species Mouse

ACPP-Antibody-C-term-Blocking-Peptide - BP7592b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Prostatic Acid Phosphatase blocking peptide - GTX88063-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

Recombinant Human Prostatic Acid Phosphatase/ACPP, CF - 6240-AP-010 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Met1-Gln379, with a C-terminal 6-His tag

Recombinant human Prostatic acid phosphatase (OPCA00909) - OPCA00909 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human ACPP His tag protein - orb84475 from Biorbyt Category Protein Prices $510.00, $748.00 Sizes 10 μg, 20 μg Source Human Species Human

Human ACPP protein - orb49605 from Biorbyt Category Protein Prices $408.00, $595.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human ACPP protein - orb245497 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

E.coli acpP protein - orb244401 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg

Prostatic Acid Phosphatase protein - orb197699 from Biorbyt Category Protein Prices $255.00, $391.00, $519.00 Sizes 10 μg, 50 μg, 100 μg Species Human

Prostatic Acid Phosphatase protein - orb81891 from Biorbyt Category Protein Prices $731.00 Sizes 1 mg Source Sample obtained from Human Seminal Fluid. Species Human

ACPP Blocking Peptide - 33R-1679 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Search more