ACPP

Gene Symbol ACPP
Entrez Gene 55
Alt Symbol 5'-NT, ACP-3, ACP3
Species Human
Gene Type protein-coding
Description acid phosphatase, prostate
Other Description 5'-nucleotidase|TMPase|ecto-5'-nucleotidase|prostatic acid phosphatase|prostatic acid phosphotase|thiamine monophosphatase
Swissprots D3DNC6 Q96QM0 Q96QK9 Q96KY0 Q5FBY0 P15309
Accessions AAA60021 AAB60640 CAA50514 CAA52913 EAW79201 EAW79202 EAW79203 EAW79204 EAW79205 P15309 AA578274 AB102888 BAD89417 AK300540 BAG62248 AW136372 BC007460 AAH07460 BC008493 AAH08493 BC016344 AAH16344 BC017877 AAH17877 BQ100881 DC383453 DQ893148 ABM84074 DQ896443 ABM87442 M24902 AAA60022 M34840 AAA69694 X52174 CAA36422 X53605 CAA37673 XM_011512946 XP_011511248 XM_011512947 XP_011511249 NM_001099 NP_001090 NM_001134194 NP_001127666 NM_001292037 NP_001278966
Function A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma.
Subcellular Location Isoform 1: Secreted.
Tissue Specificity Highly expressed in the prostate, restricted to glandular and ductal epithelial cells. Also expressed in bladder, kidney, pancreas, lung, cervix, testis and ovary. Weak expression in a subset of pancreatic islet cells, squamous epithelia, the pilosebaceous unit, colonic neuroendocrine cells and skin adnexal structures. Isoform 2 also expressed in the sarcolemma of skeletal muscle. Levels of this cellular isoform decreased in prostate cancer. {ECO:0000269|PubMed:17638863, ECO:0000269|PubMed:21487525}.
Top Pathways Riboflavin metabolism

PAcP CRISPR/Cas9 KO Plasmid (h) - sc-405118 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAcP HDR Plasmid (h) - sc-405118-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAcP Double Nickase Plasmid (h) - sc-405118-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAcP Double Nickase Plasmid (h2) - sc-405118-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAcP CRISPR Activation Plasmid (h) - sc-405118-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAcP CRISPR Activation Plasmid (h2) - sc-405118-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAcP Lentiviral Activation Particles (h) - sc-405118-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAcP Lentiviral Activation Particles (h2) - sc-405118-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAcP siRNA (h) - sc-72131 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PAcP shRNA Plasmid (h) - sc-72131-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PAcP shRNA (h) Lentiviral Particles - sc-72131-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Prostatic Acid Phosphatase/ACPP RNAi - H00000055-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU067161 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® Human Phosphatase - SIHP0017 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0018 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0016 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN2742 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2742 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ACPP siRNA (Human) - CRH0043 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ACPP - MBS8231293 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ACPP (NM_001099.4) - SHH230610 from Creative biogene

Category siRNA
Species Reactivities Human

Human ACPP siRNA - orb260545 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ACPP shRNA Plasmid (Human) - CHH0043 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ACPP miRNA 3'UTR clone - MiUTR3H-01718 from Creative biogene

Species Reactivities Human

ACPP miRNA 3'UTR clone - MiUTR3H-01719 from Creative biogene

Species Reactivities Human
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