HACE1

Gene Symbol	HACE1
Entrez Gene	57531
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
Other Description	E3 ubiquitin-protein ligase HACE1
Swissprots	B4DFM6 Q8ND12 Q5VU99 E9PGP0 B3KY89 B4DTQ4 Q5VUA0 A8K6U5 Q9P2M6 B7Z9X6 Q8IYU2
Accessions	CCQ43645 EAW48437 EAW48438 EAW48439 Q8IYU2 AB037741 BAA92558 AJ420474 AK124268 AK131207 BAG54751 AK291760 BAF84449 AK292683 BAF85372 AK294164 BAG57487 AK300314 BAG62066 AK311633 AK316091 BAH14462 AL834202 CAD38890 BC034982 AAH34982 BC038119 BC041919 DA651352 DQ891735 ABM82661 XM_006715528 XP_006715591 XM_006715529 XP_006715592 XM_006715530 XP_006715593 XM_011535989 XP_011534291 XM_011535990 XP_011534292 XM_011535991 XP_011534293 XM_011535992 XP_011534294 XR_942529 XR_942531 NM_020771 NP_065822 NR_104424
Function	E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB. {ECO:0000269|PubMed:15254018, ECO:0000269|PubMed:21988917, ECO:0000269|PubMed:22036506}.
Subcellular Location	Golgi apparatus, Golgi stack membrane. Cytoplasm. Endoplasmic reticulum. Note=A significant portion localizes to the endoplasmic reticulum. Targeted to Golgi membrane via its interaction with Rab proteins.
Tissue Specificity	Expressed in multiple tissues including heart, brain and kidney. {ECO:0000269|PubMed:15254018}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HACE1 ELISA Kit (Sandwich ELISA) - LS-F11601 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

E3 ubiquitin-protein ligase HACE1 (HACE1), Human, ELISA Kit - CSB-EL010115HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 6.25 pg/ml Range 25 pg/ml-1600 pg/ml

E3 ubiquitin-protein ligase HACE1, HACE1, Human, ELISA Kit - E4918h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1, ELISA Kit - MBS906477 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 6.25 pg/ml Range 25 pg/ml-1600 pg/ml

Human E3 ubiquitin-protein ligase HACE1(HACE1) ELISA kit - CSB-EL010115HU from Cusabio Category ELISA Kit Sensitivity 6.25 pg/ml. Range 25 pg/ml-1600 pg/ml

Bovine HACE1 ELISA Kit (Custom ELISA) - LS-F19953 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Chicken HACE1 ELISA Kit (Custom ELISA) - LS-F19950 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Rat HACE1 ELISA Kit (Custom ELISA) - LS-F19951 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Mouse HACE1 ELISA Kit (Custom ELISA) - LS-F19952 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

E3 ubiquitin-protein ligase HACE1, ELISA Kit - MBS288405 from MyBioSource Category ELISA Kit Prices $430.00, $570.00, $2,515.00, $4,520.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E3 ubiquitin-protein ligase HACE1, ELISA Kit - MBS288396 from MyBioSource Category ELISA Kit Prices $430.00, $570.00, $2,515.00, $4,520.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E3 ubiquitin-protein ligase HACE1, ELISA Kit - MBS288219 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.78 ng/ml -50.0 ng/ml.

E3 ubiquitin-protein ligase HACE1, ELISA Kit - MBS288154 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

HACE1 - EKH4596 from Nordic BioSite Sensitivity 0.094ng/ml Range 0.156-10ng/ml

HACE1 ELISA Kit (Human) (OKEH01737) - OKEH01737 from Aviva Systems Biology Category ELISA Kit Prices $420.00 Sizes 96 wells Sensitivity < 0.054 ng/mL Range 0.156 - 10 ng/mL

Human HACE1 ELISA Kit - E018082 from Biobool Category ELISA Kit Sensitivity 6.25 pg/ml

Human E3 ubiquitin-protein ligase HACE1 ELISA Kit - EK4644 from Signalway Antibody Category ELISA Kit Prices $599.00 Sizes 1x96t Sensitivity less than 10pg/mL Range 31.2-2000 pg/mL

E3 ubiquitin-protein ligase HACE1, ELISA Kit - MBS2884168 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.156-10 ng/mL

E3 ubiquitin-protein ligase HACE1, ELISA Kit - MBS764362 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/ml Range 0.156-10ng/ml

E3 ubiquitin-protein ligase HACE1, ELISA Kit - MBS9428470 from MyBioSource Category ELISA Kit Prices $555.00 Sizes 96 tests Sensitivity Less than 0.054ng/mL Range 0.156-10 ng/mL

Human HACE1 ELISA Kit (Sandwich ELISA) - LS-F33910 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.094 Range 0.156-10 ng/ml

Search more