METTL14

Gene Symbol	METTL14
Entrez Gene	57721
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	methyltransferase like 14
Other Description	N6-adenosine-methyltransferase subunit METTL14|methyltransferase-like protein 14
Swissprots	Q969V2 A6NIG1 Q9HCE5
Accessions	EAW73651 EAW73652 Q9HCE5 AB046847 BAB13453 AK055555 BAB70954 AK296056 BAG58819 AW206149 BC006565 AAH06565 BC007449 AAH07449 BG773151 HQ448248 ADQ32728 XM_005263166 XP_005263223 XM_011532162 XP_011530464 XR_938769 NM_020961 NP_066012
Function	N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and self-renewal of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing and processing and mRNA stability. M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding developmental regulators, results in transcript destabilization, maintaining the groung state of ESCs, thereby promoting self-renewal of ESCs. {ECO:0000269|PubMed:24316715, ECO:0000269|PubMed:24407421}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:24316715, ECO:0000269|PubMed:24407421}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human METTL14 full length protein - ab163640 from Abcam Category Protein Source Wheat germ Species Human

METTL14 Antibody Blocking Peptide - LS-E18288 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human METTL14 Protein - H00057721-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

METTL14 - H00057721-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

METTL14 fusion protein - ag14321 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

METTL14 fusion protein - ag14325 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Methyltransferase-like protein 14(METTL14) - CSB-YP884519HU CSB-EP884519HU CSB-BP884519HU CSB-MP884519HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

METTL14 - TP300925 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

METTL14 Recombinant Protein Antigen - NBP1-81392PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

METTL14 Peptide, Human - M34GP09426H from Creative Peptides Category Peptide Source Synthetic. Species Human

Methyltransferase-like protein 14 (METTL14), Recombinant Protein - MBS1386473 from MyBioSource Category Protein Prices $1,235.00, $1,235.00, $1,455.00, $1,455.00, $2,010.00, $2,010.00, $2,475.00, $2,475.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant METTL14 protein - 31568 from ActiveMotif Category Protein Prices $395.00 Sizes 20 µg Source Baculovirus Species Human

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