Gene Symbol | METTL14 |
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Entrez Gene | 57721 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | methyltransferase like 14 |
Other Description | N6-adenosine-methyltransferase subunit METTL14|methyltransferase-like protein 14 |
Swissprots | Q969V2 A6NIG1 Q9HCE5 |
Accessions | EAW73651 EAW73652 Q9HCE5 AB046847 BAB13453 AK055555 BAB70954 AK296056 BAG58819 AW206149 BC006565 AAH06565 BC007449 AAH07449 BG773151 HQ448248 ADQ32728 XM_005263166 XP_005263223 XM_011532162 XP_011530464 XR_938769 NM_020961 NP_066012 |
Function | N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and self-renewal of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing and processing and mRNA stability. M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding developmental regulators, results in transcript destabilization, maintaining the groung state of ESCs, thereby promoting self-renewal of ESCs. {ECO:0000269|PubMed:24316715, ECO:0000269|PubMed:24407421}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:24316715, ECO:0000269|PubMed:24407421}. |
Human METTL14 full length protein - ab163640 from Abcam
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METTL14 Antibody Blocking Peptide - LS-E18288 from LifeSpan Bioscience
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Recombinant Human METTL14 Protein - H00057721-P01 from Novus Biologicals
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METTL14 - H00057721-P01 from Acris Antibodies
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METTL14 fusion protein - ag14321 from Proteintech Group
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METTL14 fusion protein - ag14325 from Proteintech Group
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Recombinant Human Methyltransferase-like protein 14(METTL14) - CSB-YP884519HU CSB-EP884519HU CSB-BP884519HU CSB-MP884519HU from Cusabio
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METTL14 - TP300925 from Acris Antibodies
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METTL14 Recombinant Protein Antigen - NBP1-81392PEP from Novus Biologicals
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METTL14 Peptide, Human - M34GP09426H from Creative Peptides
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Methyltransferase-like protein 14 (METTL14), Recombinant Protein - MBS1386473 from MyBioSource
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Recombinant METTL14 protein - 31568 from ActiveMotif
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