METTL14

Gene Symbol METTL14
Entrez Gene 57721
Alt Symbol -
Species Human
Gene Type protein-coding
Description methyltransferase like 14
Other Description N6-adenosine-methyltransferase subunit METTL14|methyltransferase-like protein 14
Swissprots Q969V2 A6NIG1 Q9HCE5
Accessions EAW73651 EAW73652 Q9HCE5 AB046847 BAB13453 AK055555 BAB70954 AK296056 BAG58819 AW206149 BC006565 AAH06565 BC007449 AAH07449 BG773151 HQ448248 ADQ32728 XM_005263166 XP_005263223 XM_011532162 XP_011530464 XR_938769 NM_020961 NP_066012
Function N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and self-renewal of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing and processing and mRNA stability. M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding developmental regulators, results in transcript destabilization, maintaining the groung state of ESCs, thereby promoting self-renewal of ESCs. {ECO:0000269|PubMed:24316715, ECO:0000269|PubMed:24407421}.
Subcellular Location Nucleus {ECO:0000269|PubMed:24316715, ECO:0000269|PubMed:24407421}.

METTL14 (T-20) - sc-247960 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
METTL14 (T-20): sc-247960. Western blot analysis of METTL14 expression in Jurkat (A) and Hep G2 (B) whole cell lysates and mouse liver tissue extract (C).

Anti-METTL14 antibody - ab98166 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-METTL14 antibody (ab98166) at 1 µg/ml (in 5% skim milk / PBS buffer) + NCI-H226 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-METTL14 antibody - ab167243 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-METTL14 antibody (ab167243) at 1/500 dilutionLane 1 : METTL14 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.

Anti-METTL14 Antibody (aa35-84) - LS-C107729 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
METTL14 antibody LS-C107729 Western blot of NCI-H226 cell lysate.

METTL14 Antibody - NBP1-81392 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: METTL14 Antibody [NBP1-81392] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.

METTL14 Antibody - NBP1-79389 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: METTL14 Antibody [NBP1-79389] - Sample Tissue: Human PANC1 Antibody Dilution: 1.0 ug/ml

METTL14 Antibody - H00057721-B01 from Novus Biologicals

Host Mouse
Clonality Polyclonal
Western Blot: METTL14 Antibody [H00057721-B01] - analysis of KIAA1627 expression in transfected 293T cell line by KIAA1627 MaxPab polyclonal antibody. Lane 1: KIAA1627 transfected lysate (52.20 KDa). Lane 2: Non-transfected lysate.

METTL14 Antibody - H00057721-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: METTL14 Antibody [H00057721-B01P] - Analysis of KIAA1627 expression in human placenta.

Anti-KIAA1627, (N-terminal) antibody produced in rabbit - SAB2104924 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-KIAA1627, antibody produced in rabbit: <B>Cat. No. SAB2104924</B>: Immunoblotting analysis of KIAA1627 in NCI-H226 cell lysate with KIAA1627 anitbody at 1 μg/mL.

Anti-KIAA1627 antibody produced in mouse - SAB1409581 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-KIAA1627: <B>Cat. No. SAB1409581</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~52.2 kDa using KIAA1627 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-METTL14 (36-49) antibody produced in rabbit - SAB1104405 from Sigma-Aldrich

Prices $285.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human METTL14 was separated on SDS-PAGE, blotted with Anti-METTL14 (36-49) (<B>Cat. No. SAB1104405</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:250

Anti-METTL14 antibody produced in rabbit - HPA038002 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-METTL14: <B>Cat. No. HPA038002</B>: Immunohistochemical staining of human testis shows strong cytoplasmic and nuclear positivity in cells in seminiferus ducts.

KIAA1627 antibody - N-terminal region (ARP50652_P050) - ARP50652_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

METTL14 antibody - H00057721-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

KIAA1627 Antibody - GWB-MR989H from Genway Biotech

Prices $368.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-METTL14 (full length) polyclonal antibody - DPABH-06452 from Creative Diagnostics

Host Mouse
Clonality Polyclonal

Anti-METTL14 (aa 35-84) polyclonal antibody - DPABH-19879 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Anti-METTL14 monoclonal antibody - DCABH-200797 from Creative Diagnostics

Host Rabbit
Clonality Monoclonal

METTL14 - A8530 from NeoScientific

Prices $220.00, $380.00
Sizes 100 µl, 200 µl
Host Rabbit
Clonality Monoclonal

METTL14 Polyclonal Antibody - A8530 from ABclonal

Prices $130.00, $220.00, $380.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using METTL14 antibody.

Anti-METTL14 Antibody - ABE1338 from EMD Millipore

Prices $279.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

METTL14 Antibody - abx123810 from Abbexa

Host Rabbit
Clonality Polyclonal

METTL14 antibody - TA339744 from Acris Antibodies

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
WB Suggested Anti-METTL14 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: NCI-H226 cell lysate

Anti-METTL14 (C-terminal half) polyclonal antibody - CABT-B1721 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Anti-METTL14 antibody - STJ111272 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal
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