METTL14

Gene Symbol METTL14
Entrez Gene 57721
Alt Symbol -
Species Human
Gene Type protein-coding
Description methyltransferase like 14
Other Description N6-adenosine-methyltransferase subunit METTL14|methyltransferase-like protein 14
Swissprots Q969V2 A6NIG1 Q9HCE5
Accessions EAW73651 EAW73652 Q9HCE5 AB046847 BAB13453 AK055555 BAB70954 AK296056 BAG58819 AW206149 BC006565 AAH06565 BC007449 AAH07449 BG773151 HQ448248 ADQ32728 XM_005263166 XP_005263223 XM_011532162 XP_011530464 XR_938769 NM_020961 NP_066012
Function N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and self-renewal of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing and processing and mRNA stability. M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding developmental regulators, results in transcript destabilization, maintaining the groung state of ESCs, thereby promoting self-renewal of ESCs. {ECO:0000269|PubMed:24316715, ECO:0000269|PubMed:24407421}.
Subcellular Location Nucleus {ECO:0000269|PubMed:24316715, ECO:0000269|PubMed:24407421}.

METTL14 CRISPR/Cas9 KO Plasmid (h) - sc-406936 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

METTL14 HDR Plasmid (h) - sc-406936-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

METTL14 Double Nickase Plasmid (h) - sc-406936-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

METTL14 Double Nickase Plasmid (h2) - sc-406936-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

METTL14 CRISPR Activation Plasmid (h) - sc-406936-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

METTL14 CRISPR Activation Plasmid (h2) - sc-406936-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

METTL14 Lentiviral Activation Particles (h) - sc-406936-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

METTL14 Lentiviral Activation Particles (h2) - sc-406936-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

METTL14 siRNA (h) - sc-89054 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

METTL14 shRNA Plasmid (h) - sc-89054-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

METTL14 shRNA (h) Lentiviral Particles - sc-89054-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU038041 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13230 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13230 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

METTL14 siRNA (Human) - CRJ1661 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human METTL14 (NM_020961.2) - SHH340687 from Creative biogene

Category siRNA
Species Reactivities Human

Human METTL14 siRNA - orb272162 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

METTL14 shRNA Plasmid (Human) - CHJ1661 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

METTL14 miRNA 3'UTR clone - MiUTR1H-05276 from Creative biogene

Species Reactivities Human
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