UBXN6

Gene Symbol UBXN6
Entrez Gene 80700
Alt Symbol UBXD1, UBXDC2
Species Human
Gene Type protein-coding
Description UBX domain protein 6
Other Description UBX domain containing 1|UBX domain-containing 1|UBX domain-containing 2|UBX domain-containing protein 1|UBX domain-containing protein 6
Swissprots Q9BZV1 Q96AH1 Q96IK9 D6W626 Q9BZV0
Accessions EAW69219 EAW69220 EAW69221 EAW69222 EAW69223 Q9BZV1 AF272893 AAK13257 AF272894 AAK13258 AK090473 BAC03454 AL833695 BC007414 AAH07414 BC008288 AAH08288 BC017113 AAH17113 BM764980 XR_936205 NM_001171091 NP_001164562 NM_025241 NP_079517
Function Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. MDM2 stabilization leads to MDM2-dependent TP53 degradation. {ECO:0000269|PubMed:18768758}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:18656546}. Nucleus {ECO:0000269|PubMed:18656546}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:18656546}. Note=Localizes at the centrosome both in interphase and during mitosis.
Tissue Specificity Enhanced expression in testis.
Top Pathways Protein processing in endoplasmic reticulum

UBXN6-Over-expression-Lysate - LY14967a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag UBXN6 (arrow) using his tag antibody. 293T cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the UBXN6 gene‘

UBXN6 Overexpression Lysate (Native) - NBP2-06215 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg

Panoply™ Human UBXN6 Knockdown Stable Cell Line - CSC-DC017018 from Creative biogene

Category Cell Line
Species Human

UBXN6 KO Cell Lysate-HEK293T - CLKO-0738 from Creative biogene

Category Cell Lysate
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