UBXN6

Gene Symbol UBXN6
Entrez Gene 80700
Alt Symbol UBXD1, UBXDC2
Species Human
Gene Type protein-coding
Description UBX domain protein 6
Other Description UBX domain containing 1|UBX domain-containing 1|UBX domain-containing 2|UBX domain-containing protein 1|UBX domain-containing protein 6
Swissprots Q9BZV1 Q96AH1 Q96IK9 D6W626 Q9BZV0
Accessions EAW69219 EAW69220 EAW69221 EAW69222 EAW69223 Q9BZV1 AF272893 AAK13257 AF272894 AAK13258 AK090473 BAC03454 AL833695 BC007414 AAH07414 BC008288 AAH08288 BC017113 AAH17113 BM764980 XR_936205 NM_001171091 NP_001164562 NM_025241 NP_079517
Function Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. MDM2 stabilization leads to MDM2-dependent TP53 degradation. {ECO:0000269|PubMed:18768758}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:18656546}. Nucleus {ECO:0000269|PubMed:18656546}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:18656546}. Note=Localizes at the centrosome both in interphase and during mitosis.
Tissue Specificity Enhanced expression in testis.
Top Pathways Protein processing in endoplasmic reticulum

UBXD1 (L-16) - sc-244563 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
UBXD1 (L-16): sc-244563. Western blot analysis of UBXD1 expression in PC-3 whole cell lysate (A) and human skeletal muscle tissue extract (B).

Anti-UBXN6 antibody - ab103526 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human ovarian carcinoma tissue labelling UBXN6 with ab103526 at 1/1000 (1µg/ml). Detection: DAB.

Anti-UBXN6 antibody - ab103651 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-UBXN6 antibody (ab103651) at 1/100 dilution + Mouse kidney tissue lysates at 35 µg

Anti-UBXN6 antibody - ab103525 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human ovarian carcinoma tissue labelling UBXN6 with ab103525 at 1/1000 (1µg/ml). Detection: DAB.

Anti-UBXN6 antibody - ab128287 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-UBXN6 antibody (ab128287) at 1 µg/ml + Mouse heart lysate at 10 µgdeveloped using the ECL technique

Anti-UBXN6 antibody [2F8-24] - ab81555 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2F8-24
All lanes : Anti-UBXN6 antibody [2F8-24] (ab81555) at 1 µg/mlLane 1 : U20S cells transfected with UBXN6 shRNALane 2 : U20S cells transfected with mismatch control shRNA

Anti-UBXN6 antibody [5C3-1] - ab80659 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 5C3-1
Lanes 1 - 2 : Anti-UBXN6 antibody [5C3-1] (ab80659) at 0.3 µg/ml (in PBS/Tween)Lanes 3 - 4 : Ponceau S RedLane 1 : U2OS were co-transfected with pBabepuro and pSuper based plasmid encoding anti- UBXD1 shRNALane 2 : U2OS were co-transfected with mismatch controlLane 3 : U2OS were co-transfected with pBabepuro and pSuper based plasmid encoding anti- UBXD1 shRNALane 4 : U2OS were co-transfected with mismatch controlObserved band size : 54 kDa (why is the actual band size different from the predicted?)Additional bands at : 49 kDa (possible isoform).

Anti-UBXN6 / UBXD1 Antibody (aa391-441) - LS-C289640 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human UBXD1 by Immunohistochemistry. Samples: FFPE serial sections of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-UBXD1 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.

Anti-UBXN6 / UBXD1 Antibody - LS-C93238 from LifeSpan Bioscience

Prices $495.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-UBXN6 / UBXD1 Antibody - LS-C93239 from LifeSpan Bioscience

Prices $495.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-UBXN6 / UBXD1 Antibody (aa301-350) - LS-C151357 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
UBXN6 / UBXD1 antibody Western Blot of Mouse Heart.

Anti-UBXN6 / UBXD1 Antibody (aa281-309, AP) - LS-C207833 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBXN6 / UBXD1 Antibody (aa281-309, APC) - LS-C207834 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBXN6 / UBXD1 Antibody (aa281-309, Biotin) - LS-C207835 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBXN6 / UBXD1 Antibody (aa301-350) - LS-C116942 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
UBXN6 antibody LS-C116942 Western blot of Fetal Muscle lysate.

Anti-UBXN6 / UBXD1 Antibody (aa281-309, FITC) - LS-C207836 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBXN6 / UBXD1 Antibody (aa281-309, PE) - LS-C207838 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBXN6 / UBXD1 Antibody (aa281-309, Azide-free, HRP) - LS-C207837 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBXN6 / UBXD1 Antibody (aa290-320) - LS-C326163 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBXN6 / UBXD1 Antibody (aa250-300) - LS-C289639 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human UBXD1 by Immunohistochemistry. Samples: FFPE serial sections of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-UBXD1 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.

Anti-UBXN6 / UBXD1 Antibody (aa281-309) - LS-C160406 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
UBXN6 Antibody IHC of formalin-fixed and paraffin-embedded mouse testis tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

UBXN6 Antibody - NBP1-80649 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: UBXN6 Antibody [NBP1-80649] - Staining of human testis shows strong cytoplasmic positivity in spermatids.

UBXN6 Antibody - NBP1-80648 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: UBXN6 Antibody [NBP1-80648] - Staining of human testis shows nuclear and cytoplasmic positivity in cells in seminiferous ducts and Leydig cells.

Anti-UBXN6 antibody produced in rabbit - HPA040906 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-UBXN6: <B>Cat. No. HPA040906</B>: Immunohistochemical staining of human testis shows strong cytoplasmic positivity in spermatids.

Anti-UBXN6 antibody produced in rabbit - HPA041313 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-UBXN6: <B>Cat. No. HPA041313</B>: Immunohistochemical staining of human pancreas shows strong nuclear and cytoplasmic positivity in exocrine glandular cells.
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