IL10RB

Gene Symbol	IL10RB
Entrez Gene	3588
Alt Symbol	CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2
Species	Human
Gene Type	protein-coding
Description	interleukin 10 receptor, beta
Other Description	IL-10 receptor subunit beta|IL-10R subunit 2|IL-10R subunit beta|IL-10RB|cytokine receptor class-II CRF2-4|cytokine receptor class-II member 4|cytokine receptor family 2 member 4|cytokine receptor family II, member 4|interleukin-10 receptor subunit 2|interleukin-10 receptor subunit beta
Swissprots	Q9BUU4 Q08334
Accessions	AAA86872 AAP72016 EAX09840 EAX09841 Q08334 AI025402 AK124057 BAC85761 AK299961 BAG61787 AK313348 AU133530 BC001903 AAH01903 BT009777 AAP88779 DQ892552 ABM83478 DQ895763 ABM86689 JN591378 AEX60807 Z17227 CAA78933 NM_000628 NP_000619
Function	Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. {ECO:0000269|PubMed:12469119, ECO:0000269|PubMed:15123776}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Toxoplasmosis, Tuberculosis, Epstein-Barr virus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IL-10 R beta (NP_000619) VersaClone cDNA - RDC1247 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

IL10RB - MBS1268888 from MyBioSource Species Human Accession BC001903

Human IL10RB ORF Clone(NM_000628.4) - CDCL167035 from Creative Biomart Species Human Accession NM_000628.4

Human IL10Rb Gene cDNA clone plasmid - HG10945-M from Sino Biological Species Human

Human IL10RB / IL-10RB Gene ORF cDNA clone expression plasmid, N-HA tag - HG10945-NY from Sino Biological Species Human

Human IL10Rb ORF mammalian expression plasmid, Flag tag - HG10945-M-F from Sino Biological Species Human Accession NM_000628.3

Human IL10RB / IL-10RB Gene ORF cDNA clone expression plasmid, C-His tag - HG10945-CH from Sino Biological Species Human

Human IL10RB / IL-10RB Gene ORF cDNA clone expression plasmid - HG10945-UT from Sino Biological Species Human

Human IL10RB / IL-10RB Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10945-ACG from Sino Biological Species Human

Human IL10RB / IL-10RB Gene ORF cDNA clone expression plasmid - HG10945-M-N from Sino Biological Species Human

Human IL10RB / IL-10RB Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10945-NF from Sino Biological Species Human

Human IL10RB / IL-10RB Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10945-NM from Sino Biological Species Human

Human IL10RB / IL-10RB Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10945-CF from Sino Biological Species Human

Human IL10RB / IL-10RB Gene ORF cDNA clone expression plasmid, C-HA tag - HG10945-CY from Sino Biological Species Human

Human IL10RB / IL-10RB Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10945-CM from Sino Biological Species Human

Human IL10RB / IL-10RB Gene ORF cDNA clone expression plasmid, N-His tag - HG10945-NH from Sino Biological Species Human

Mouse IL-10 R beta (NP_032375) VersaClone cDNA - RDC1446 from R&D Systems Prices $199.00 Sizes 10 µg Species Mouse

Human IL10RB ORF Clone (BC001903) - CDCS405803 from Creative biogene Species Human Accession Q08334

Human IL10RB ORF clone (NM_000628.3) - CDCB157482 from Creative biogene Species Human

Human IL10RB / IL-10RB Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10945-ACR from Sino Biological Species Human

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