IL10RB

Gene Symbol	IL10RB
Entrez Gene	3588
Alt Symbol	CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2
Species	Human
Gene Type	protein-coding
Description	interleukin 10 receptor, beta
Other Description	IL-10 receptor subunit beta|IL-10R subunit 2|IL-10R subunit beta|IL-10RB|cytokine receptor class-II CRF2-4|cytokine receptor class-II member 4|cytokine receptor family 2 member 4|cytokine receptor family II, member 4|interleukin-10 receptor subunit 2|interleukin-10 receptor subunit beta
Swissprots	Q9BUU4 Q08334
Accessions	AAA86872 AAP72016 EAX09840 EAX09841 Q08334 AI025402 AK124057 BAC85761 AK299961 BAG61787 AK313348 AU133530 BC001903 AAH01903 BT009777 AAP88779 DQ892552 ABM83478 DQ895763 ABM86689 JN591378 AEX60807 Z17227 CAA78933 NM_000628 NP_000619
Function	Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. {ECO:0000269|PubMed:12469119, ECO:0000269|PubMed:15123776}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Toxoplasmosis, Tuberculosis, Epstein-Barr virus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IL10RB protein fragment - ab191962 from Abcam Category Protein Source HEK 293 cells Species Human

Human IL10RB protein fragment - ab126022 from Abcam Category Protein Source E. coli Species Human

Recombinant Human IL-10 R beta Protein - H00003588-G01 from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Source Wheat Germ Species Human

Recombinant Human IL-10 R beta Fc Chimera, CF - 874-RB-100 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Human IL-10RB protein - orb180303 from Biorbyt Category Protein Prices $213.00, $408.00, $850.00, $1,088.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Source Human Cells Species Human

Human IL-10RB protein - orb180302 from Biorbyt Category Protein Prices $196.00, $366.00, $1,012.00, $1,309.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human IL10Rb Protein - abx067428 from Abbexa Category Protein Source E.coli Species Human

CDw210b / IL10RB - H00003588-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

CDw210b / IL10RB - H00003588-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CDw210b / IL10RB - H00003588-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Interleukin 10 Receptor Beta (IL10Rb), Human - 20-7873 from ARP American Research Products Category Protein Prices $585.00 Sizes 50 µg Source E.coli Species Human

IL10RB fusion protein - Ag7468 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

IL10RB fusion protein - ag7445 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human IL10RB, Fc-His tagged - IL10RB-176H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human IL10RB, His tagged - IL10RB-2251H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human IL10RB, His-tagged - IL10RB-14142H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human IL10RB, MIgG2a Fc-tagged - IL10RB-201H from Creative Biomart Category Protein Source CHO cell Species Human

Recombinant Human IL10RB, HIgG1 Fc-tagged - IL10RB-202H from Creative Biomart Category Protein Source CHO cell Species Human

Recombinant Human IL10RB, HIgG1 Fc-tagged - IL10RB-203H from Creative Biomart Category Protein Source CHO cell Species Human

Recombinant Human Interleukin 10 Receptor, Beta - IL10RB-1647H from Creative Biomart Category Protein Source NSO Cells.

Human IL-10 receptor beta (IL10RB) Recombinant - RKQ08334 from Reprokine Category Protein Prices $280.00, $620.00, $2,750.00 Sizes 50 µg, 200 µg, 1 mg Source DNA sequence encoding extracellular domain of human IL-10RB fused to a C-terminal polyHis tag was expressed in HEK cells. Species Human

Recombinant Interleukin 10 Receptor Beta (IL10Rb) - RPB638Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Interleukin 10 Receptor Beta (IL10Rb) - RPB638Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Interleukin 10 Receptor Beta (IL10Rb) - RPB638Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Human IL10Rb Protein (His & Fc Tag) - 10945-H03H-100 from Sino Biological Category Protein Prices $198.00, $348.00 Sizes 100 µg, 200 µg Source Human Cells Species Human

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