Gene Symbol | ARTN |
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Entrez Gene | 9048 |
Alt Symbol | ENOVIN, EVN, NBN |
Species | Human |
Gene Type | protein-coding |
Description | artemin |
Other Description | neublastin|neurotrophic factor |
Swissprots | Q6P6A3 D3DPY3 Q5T4W7 D3DPY1 O96030 O95441 |
Accessions | AAD13109 AAD13110 CAB52396 EAX07074 EAX07075 EAX07076 EAX07077 EAX07078 EAX07079 EAX07080 EAX07081 Q5T4W7 AF109401 AAC98690 AF120274 AAD21075 BC062375 AAH62375 XM_006711024 XP_006711087 XM_011542402 XP_011540704 NM_001136215 NP_001129687 NM_057090 NP_476431 NM_057091 NP_476432 NM_003976 NM_057160 |
Function | Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue. {ECO:0000269|PubMed:10583383, ECO:0000269|PubMed:9883723}. |
Subcellular Location | Secreted {ECO:0000250}. |
Tissue Specificity | Ubiquitous. Expressed at high levels in peripheral tissues including prostate, placenta, pancreas, heart, kidney, pituitary gland, lung and testis. Expressed at low levels in the brain. {ECO:0000269|PubMed:10583383, ECO:0000269|PubMed:9883723}. |
Artn (C-18) - sc-9330 from Santa Cruz Biotechnology
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Artn (N-18) - sc-9329 from Santa Cruz Biotechnology
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Artn (R-17) - sc-9331 from Santa Cruz Biotechnology
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Artn L (G-19) - sc-9332 from Santa Cruz Biotechnology
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Anti-Artemin antibody - ab203041 from Abcam
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Anti-Artemin antibody - ab109812 from Abcam
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Anti-Artemin antibody - ab189360 from Abcam
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Anti-Artemin antibody - ab91009 from Abcam
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Anti-Artemin antibody - ab169706 from Abcam
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Anti-Artemin antibody - ab109567 from Abcam
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Anti-Artemin antibody (Biotin) - ab84237 from Abcam
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Anti-Artemin antibody [EPR9763] - ab178434 from Abcam
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Anti-Artemin antibody - Aminoterminal end - ab45506 from Abcam
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Anti-ARTN / Artemin Antibody (N-Terminus) - LS-C40581 from LifeSpan Bioscience
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Anti-ARTN / Artemin Antibody (Biotin) - LS-C104373 from LifeSpan Bioscience
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Anti-ARTN / Artemin Antibody (aa112-224, Biotin) - LS-C299164 from LifeSpan Bioscience
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Anti-ARTN / Artemin Antibody (aa77-126) - LS-C151576 from LifeSpan Bioscience
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Anti-ARTN / Artemin Antibody (aa112-224, Biotin) - LS-C299165 from LifeSpan Bioscience
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Anti-ARTN / Artemin Antibody (aa112-224, FITC) - LS-C302337 from LifeSpan Bioscience
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Anti-ARTN / Artemin Antibody (aa112-224, FITC) - LS-C302540 from LifeSpan Bioscience
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Anti-ARTN / Artemin Antibody (aa112-224) - LS-C294030 from LifeSpan Bioscience
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Anti-ARTN / Artemin Antibody (aa112-224) - LS-C292943 from LifeSpan Bioscience
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Anti-ARTN / Artemin Antibody (aa219-229) - LS-C139700 from LifeSpan Bioscience
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Anti-ARTN / Artemin Antibody (aa127-140) IHC-plus⢠- LS-B5083 from LifeSpan Bioscience
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Anti-ARTN / Artemin Antibody (aa110-123) IHC-plus⢠- LS-B234 from LifeSpan Bioscience
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