Gene Symbol | ARTN |
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Entrez Gene | 9048 |
Alt Symbol | ENOVIN, EVN, NBN |
Species | Human |
Gene Type | protein-coding |
Description | artemin |
Other Description | neublastin|neurotrophic factor |
Swissprots | Q6P6A3 D3DPY3 Q5T4W7 D3DPY1 O96030 O95441 |
Accessions | AAD13109 AAD13110 CAB52396 EAX07074 EAX07075 EAX07076 EAX07077 EAX07078 EAX07079 EAX07080 EAX07081 Q5T4W7 AF109401 AAC98690 AF120274 AAD21075 BC062375 AAH62375 XM_006711024 XP_006711087 XM_011542402 XP_011540704 NM_001136215 NP_001129687 NM_057090 NP_476431 NM_057091 NP_476432 NM_003976 NM_057160 |
Function | Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue. {ECO:0000269|PubMed:10583383, ECO:0000269|PubMed:9883723}. |
Subcellular Location | Secreted {ECO:0000250}. |
Tissue Specificity | Ubiquitous. Expressed at high levels in peripheral tissues including prostate, placenta, pancreas, heart, kidney, pituitary gland, lung and testis. Expressed at low levels in the brain. {ECO:0000269|PubMed:10583383, ECO:0000269|PubMed:9883723}. |
Human Artemin protein fragment - ab50124 from Abcam
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ARTN / Artemin Antibody Blocking Peptide - LS-E27452 from LifeSpan Bioscience
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ARTN / Artemin Antibody Blocking Peptide - LS-E23309 from LifeSpan Bioscience
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Artemin Recombinant Protein - H00009048-P01 from Novus Biologicals
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Recombinant Human Artemin Protein - P4372 from Novus Biologicals
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Recombinant Human Artemin Protein - NBP1-99264 from Novus Biologicals
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Artemin recombinant protein - GTX65299 from GeneTex
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Artemin Recombinant Protein (Active) - GTX48333-PRO from GeneTex
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Neurotrophin 3 Recombinant Protein (Active) - GTX48391-PRO from GeneTex
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Recombinant Human Artemin - 2589-AR-025 from R&D Systems
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Recombinant Human Artemin, CF - 2589-AR-025/CF from R&D Systems
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Artemin Protein (OPPA00571) - OPPA00571 from Aviva Systems Biology
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Recombinant Artemin (OPSD00022) - OPSD00022 from Aviva Systems Biology
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Human Artemin protein - orb80269 from Biorbyt
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Human Artemin protein - orb176062 from Biorbyt
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Artemin protein - 30R-AA043 from Fitzgerald
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Artemin Peptide - AC21-2276-P from Abcore
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Artemin - PA181 from Acris Antibodies
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Artemin - PA181X from Acris Antibodies
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Artemin - H00009048-P01 from Acris Antibodies
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Artemin - P4372 from Acris Antibodies
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Artemin, Recombinant Human - 213-10024-1 from RayBiotech
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Recombinant Human Artemin - 213-10024-2 from RayBiotech
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ARTN Peptide - 42-639P from ProSci
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Artemin Recombinant Protein - 40-113 from ProSci
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