NUDT15

Gene Symbol	NUDT15
Entrez Gene	55270
Alt Symbol	MTH2
Species	Human
Gene Type	protein-coding
Description	nudix (nucleoside diphosphate linked moiety X)-type motif 15
Other Description	8-oxo-dGTPase NUDT15|mutT homolog 2|probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15|probable 8-oxo-dGTP diphosphatase NUDT15
Swissprots	Q6P2C9 A2RUR6 Q32Q27 Q9NV35
Accessions	EAX08782 Q9NV35 AK001818 BAA91925 BC050698 BC064607 AAH64607 BC107875 AAI07876 BC133015 AAI33016 BC133017 AAI33018 BU622058 NM_001304745 NP_001291674 NM_018283 NP_060753
Function	Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear (By similarity). May have a role in DNA synthesis and cell cycle progression through the interaction with PCNA. {ECO:0000250, ECO:0000269|PubMed:19419956, ECO:0000269|PubMed:22556419}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

NUDT15 Antibody Blocking Peptide - LS-E686 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NUDT15 Antibody Blocking Peptide - LS-E17654 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NUDT15-Antibody-C-term-Blocking-peptide - BP11030b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Probable 8-oxo-dGTP diphosphatase NUDT15(NUDT15) - CSB-YP885733HU CSB-EP885733HU CSB-BP885733HU CSB-MP885733HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NUDT15 Protein - abx163211 from Abbexa Category Protein Species Human

NUDT15 - TP310477 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Probable 8-oxo-dGTP diphosphatase NUDT15 (NUDT15), Recombinant Protein - MBS1307619 from MyBioSource Category Protein Prices $905.00, $905.00, $1,130.00, $1,130.00, $1,340.00, $1,340.00, $1,795.00, $1,795.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human NUDT15 Protein, His-tagged - NUDT15-133H from Creative Biomart Category Protein Source E.coli Species Human

NUDT15 Recombinant Protein Antigen - NBP2-38436PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NUDT15 Peptide, Human - M34GP10707H from Creative Peptides Category Peptide Source Synthetic. Species Human

NUDT15 fusion protein - Ag23242 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

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