Gene Symbol | NUDT15 |
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Entrez Gene | 55270 |
Alt Symbol | MTH2 |
Species | Human |
Gene Type | protein-coding |
Description | nudix (nucleoside diphosphate linked moiety X)-type motif 15 |
Other Description | 8-oxo-dGTPase NUDT15|mutT homolog 2|probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15|probable 8-oxo-dGTP diphosphatase NUDT15 |
Swissprots | Q6P2C9 A2RUR6 Q32Q27 Q9NV35 |
Accessions | EAX08782 Q9NV35 AK001818 BAA91925 BC050698 BC064607 AAH64607 BC107875 AAI07876 BC133015 AAI33016 BC133017 AAI33018 BU622058 NM_001304745 NP_001291674 NM_018283 NP_060753 |
Function | Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear (By similarity). May have a role in DNA synthesis and cell cycle progression through the interaction with PCNA. {ECO:0000250, ECO:0000269|PubMed:19419956, ECO:0000269|PubMed:22556419}. |
NUDT15 (G-17) - sc-84533 from Santa Cruz Biotechnology
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Anti-NUDT15 antibody - ab122521 from Abcam
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Anti-NUDT15 antibody - ab122958 from Abcam
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Anti-NUDT15 Antibody (aa89-118, AP) - LS-C238208 from LifeSpan Bioscience
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Anti-NUDT15 Antibody (aa89-118, Biotin) - LS-C238209 from LifeSpan Bioscience
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Anti-NUDT15 Antibody (aa89-118, APC) - LS-C238210 from LifeSpan Bioscience
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Anti-NUDT15 Antibody (aa89-118, FITC) - LS-C246665 from LifeSpan Bioscience
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Anti-NUDT15 Antibody (aa89-118, PE) - LS-C246666 from LifeSpan Bioscience
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Anti-NUDT15 Antibody (aa89-118, Azide-free, HRP) - LS-C248961 from LifeSpan Bioscience
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Anti-NUDT15 Antibody (aa89-118) - LS-C323479 from LifeSpan Bioscience
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Anti-NUDT15 Antibody (aa33-82) - LS-C146099 from LifeSpan Bioscience
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Anti-NUDT15 Antibody (aa89-118) - LS-C163055 from LifeSpan Bioscience
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NUDT15 Antibody - NBP1-83800 from Novus Biologicals
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NUDT15 Antibody - NBP2-38436 from Novus Biologicals
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Anti-NUDT15 (96-110) antibody produced in rabbit - SAB1102556 from Sigma-Aldrich
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Anti-NUDT15 (141-155) antibody produced in rabbit - SAB1102557 from Sigma-Aldrich
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Anti-NUDT15 antibody produced in rabbit - HPA038968 from Sigma-Aldrich
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NUDT15 Antibody - C-terminal region (OAAB01050) - OAAB01050 from Aviva Systems Biology
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NUDT15-Antibody-C-term - AP11030b from Abgent, a WuXi AppTec company
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NUDT15 (C-term) antibody - AP52959PU-N from Acris Antibodies
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Rabbit Anti-Human NUDT15 Polyclonal Antibody - DPABH-20827 from Creative Diagnostics
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NUDT15 Polyclonal Antibody - PA5-24507 from Thermo Fisher Scientific
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NUDT15, Polyclonal Antibody - MBS6011844 from MyBioSource
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NUDT15, Polyclonal Antibody - MBS9201195 from MyBioSource
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Anti-NUDT15 antibody - STJ110666 from St John's Laboratory Ltd
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