NUDT15

Gene Symbol NUDT15
Entrez Gene 55270
Alt Symbol MTH2
Species Human
Gene Type protein-coding
Description nudix (nucleoside diphosphate linked moiety X)-type motif 15
Other Description 8-oxo-dGTPase NUDT15|mutT homolog 2|probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15|probable 8-oxo-dGTP diphosphatase NUDT15
Swissprots Q6P2C9 A2RUR6 Q32Q27 Q9NV35
Accessions EAX08782 Q9NV35 AK001818 BAA91925 BC050698 BC064607 AAH64607 BC107875 AAI07876 BC133015 AAI33016 BC133017 AAI33018 BU622058 NM_001304745 NP_001291674 NM_018283 NP_060753
Function Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear (By similarity). May have a role in DNA synthesis and cell cycle progression through the interaction with PCNA. {ECO:0000250, ECO:0000269|PubMed:19419956, ECO:0000269|PubMed:22556419}.

NUDT15 (G-17) - sc-84533 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-NUDT15 antibody - ab122521 from Abcam

Host Rabbit
Clonality Polyclonal
Immunofluorescent staining of Human cell line U-2 OS shows positivity in nucleus but not nucleoli. Recommended concentration of ab122521 1-4 µg/ml. Cells treated with PFA/Triton X-100.

Anti-NUDT15 antibody - ab122958 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-NUDT15 antibody (ab122958) at 1 µg/ml + Mouse small intestine lysate at 10 µg

Anti-NUDT15 Antibody (aa89-118, AP) - LS-C238208 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NUDT15 Antibody (aa89-118, Biotin) - LS-C238209 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NUDT15 Antibody (aa89-118, APC) - LS-C238210 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NUDT15 Antibody (aa89-118, FITC) - LS-C246665 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NUDT15 Antibody (aa89-118, PE) - LS-C246666 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NUDT15 Antibody (aa89-118, Azide-free, HRP) - LS-C248961 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NUDT15 Antibody (aa89-118) - LS-C323479 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NUDT15 Antibody (aa33-82) - LS-C146099 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
NUDT15 antibody LS-C146099 Western blot of Small Intestine lysate. Antibody concentration 1 ug/ml.

Anti-NUDT15 Antibody (aa89-118) - LS-C163055 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
NUDT15 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human breast tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

NUDT15 Antibody - NBP1-83800 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Western Blot: NUDT15 Antibody [NBP1-83800] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4

NUDT15 Antibody - NBP2-38436 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: NUDT15 Antibody [NBP2-38436] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells.

Anti-NUDT15 (96-110) antibody produced in rabbit - SAB1102556 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human NUDT15 was separated on SDS-PAGE, blotted with Anti-NUDT15 (96-110) (<B>Cat. No. SAB1102556</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000

Anti-NUDT15 (141-155) antibody produced in rabbit - SAB1102557 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human NUDT15 was separated on SDS-PAGE, blotted with Anti-NUDT15 (141-155) (<B>Cat. No. SAB1102557</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000 <BR/>2. Antibody dilution 1:1,000 + NUDT15 immunizing peptide (human, 141-155)

Anti-NUDT15 antibody produced in rabbit - HPA038968 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NUDT15: <B>Cat. No. HPA038968</B>: Immunohistochemical staining of human breast shows moderate cytoplasmic positivity in glandular cells.

NUDT15 Antibody - C-terminal region (OAAB01050) - OAAB01050 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

NUDT15-Antibody-C-term - AP11030b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
NUDT15 antibody (C-term) (Cat. #AP11030b) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the NUDT15 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

NUDT15 (C-term) antibody - AP52959PU-N from Acris Antibodies

Prices $330.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis in human breast tissuee (Formalin-fixed, Paraffin-embedded) using NUDT15 antibody Cat.-No. AP52959PU-N (C-term), followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the NUDT15 antibody  for IHC. Clinical relevance has not been evaluated.

Rabbit Anti-Human NUDT15 Polyclonal Antibody - DPABH-20827 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

NUDT15 Polyclonal Antibody - PA5-24507 from Thermo Fisher Scientific

Prices $349.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis in formalin-fixed, paraffin-embedded human breast tissue using a NUDT15 polyclonal antibody (Product ## PA5-24507), followed by HRP-conjugated secondary antibody and DAB staining.

NUDT15, Polyclonal Antibody - MBS6011844 from MyBioSource

Prices $550.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

NUDT15, Polyclonal Antibody - MBS9201195 from MyBioSource

Prices $155.00, $340.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal

Anti-NUDT15 antibody - STJ110666 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal
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