GRK1

Gene Symbol	GRK1
Entrez Gene	6011
Alt Symbol	GPRK1, RHOK, RK
Species	Human
Gene Type	protein-coding
Description	G protein-coupled receptor kinase 1
Other Description	rhodopsin kinase
Swissprots	Q15835 Q53X14
Accessions	AAC97160 AAC97161 AAQ94192 AAT00534 EAX09222 Q15835 AK289912 BAF82601 BC140945 AAI40946 BM702747 BX647503 L77503 AAG50439 U63973 AAB05929 NM_002929 NP_002920
Function	Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination. {ECO:0000269|PubMed:15946941}.
Subcellular Location	Membrane {ECO:0000250|UniProtKB:P28327}; Lipid-anchor {ECO:0000250|UniProtKB:P28327}.
Tissue Specificity	Retinal-specific. Expressed in rods and cones cells. {ECO:0000269|PubMed:11717351}.
Top Pathways	Endocytosis, Chemokine signaling pathway, Phototransduction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human GRK1 full length protein - ab105126 from Abcam Category Protein Prices $302.00, $352.00 Sizes 5 µg, 10 µg Source Baculovirus infected sf9 cells Species Human

Human GRK1 protein fragment - ab159349 from Abcam Category Protein Source Wheat germ Species Human

Rhodopsin Kinase / GRK1 Antibody Blocking Peptide - LS-E21880 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Rhodopsin Kinase / GRK1 Antibody Blocking Peptide - LS-E8597 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human GRK1 Protein - H00006011-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

GRK1 Peptide - P2086 from Novus Biologicals Category Peptide Species Human

GRK1-Antibody-C-term-Blocking-Peptide - BP7003a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GRK1 Blocking Peptide - 33R-6739 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MAPK14 protein (His tag) - 80R-2042 from Fitzgerald Category Protein Prices $365.00 Sizes 100 µg Source E.coli

Rhodopsin kinase - H00006011-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Rhodopsin kinase - H00006011-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

GRK1 fusion protein - ag19193 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

GRK1 fusion protein - ag18063 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human GRK1 - GRK1-27928TH from Creative Biomart Category Protein Source Baculovirus infected sf9 cells

Recombinant Human G Protein-Coupled Receptor Kinase 1, GST-tagged - GRK1-1018H from Creative Biomart Category Protein Species Human

Recombinant Human GRK1 (Active), GST-tagged - GRK1-1409H from Creative Biomart Category Protein Source Sf9 Cells Species Human

GRK1, active - 14-935-K from EMD Millipore Source N-terminal 6His-tagged, recombinant, human GRK1 full length, expressed by baculovirus in Sf21 insect cells Species Human

GRK1, active - 14-935 from EMD Millipore Prices $380.00 Sizes 10 µg also available in 250μg size as catalog # 14-935m and in bulk as catalog # 14-935-k. Source N-terminal 6His-tagged, recombinant, human GRK1 full length, expressed by baculovirus in Sf21 insect cells

GRK1 (A17) Peptide - BS3251P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Rhodopsin kinase(GRK1) - CSB-YP623016HU CSB-EP623016HU CSB-BP623016HU CSB-MP623016HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Rhodopsin kinase - TP314569 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

GRK1, active - 14-935M from EMD Millipore Prices $2,441.00 Sizes 250 µg also available in 10μg size as catalog # 14-935 and in bulk as catalog # 14-935-k. Source N-terminal 6His-tagged, recombinant, human GRK1 full length, expressed by baculovirus in Sf21 insect cells

GRK1 Peptide, Human - M34GP06669H from Creative Peptides Category Peptide Source Synthetic. Species Human

GRK1 Recombinant Protein Antigen - NBP2-55732PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

GRK1 Recombinant Protein Antigen - NBP2-55226PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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