| Gene Symbol |
KDM5D
|
| Entrez Gene |
8284
|
| Alt Symbol |
HY, HYA, JARID1D, SMCY
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
lysine (K)-specific demethylase 5D
|
| Other Description |
H-Y|Jumonji, AT rich interactive domain 1D (RBP2-like)|SMC homolog, Y chromosome|Smcy homolog, Y-linked|histocompatibility Y antigen|histone demethylase JARID1D|jumonji/ARID domain-containing protein 1D|lysine-specific demethylase 5D|protein SmcY|selected mouse cDNA on Y, human homolog of
|
| Swissprots |
A6H8V7 Q9BY66 Q9HCU1 Q92809 B7ZLX1 A2RU19 Q92509
|
| Accessions |
AAG00951 AAK27839 EAW54663 EAW54664 Q9BY66 AA864889 AK095923 AK127269 BAG54468 AK304027 BAG64942 BC011053 BC132721 AAI32722 BC144101 BC144102 AAI44103 BC146767 AAI46768 BM052719 BM455812 BX648643 D87072 BAA13241 DA940867 U52191 AAC50806 U52365 AAC51135 XM_005262560 XP_005262617 XM_005262561 XP_005262618 XM_005262562 XP_005262619 XM_011531468 XP_011529770 XR_244571 XR_430568 XR_938609 XR_938610 NM_001146705 NP_001140177 NM_001146706 NP_001140178 NM_004653 NP_004644
|
| Function |
Histone demethylase that specifically demethylates 'Lys- 4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis. {ECO:0000269|PubMed:17320160, ECO:0000269|PubMed:17320162, ECO:0000269|PubMed:17351630}.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|