Gene Symbol | KDM5D |
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Entrez Gene | 8284 |
Alt Symbol | HY, HYA, JARID1D, SMCY |
Species | Human |
Gene Type | protein-coding |
Description | lysine (K)-specific demethylase 5D |
Other Description | H-Y|Jumonji, AT rich interactive domain 1D (RBP2-like)|SMC homolog, Y chromosome|Smcy homolog, Y-linked|histocompatibility Y antigen|histone demethylase JARID1D|jumonji/ARID domain-containing protein 1D|lysine-specific demethylase 5D|protein SmcY|selected mouse cDNA on Y, human homolog of |
Swissprots | A6H8V7 Q9BY66 Q9HCU1 Q92809 B7ZLX1 A2RU19 Q92509 |
Accessions | AAG00951 AAK27839 EAW54663 EAW54664 Q9BY66 AA864889 AK095923 AK127269 BAG54468 AK304027 BAG64942 BC011053 BC132721 AAI32722 BC144101 BC144102 AAI44103 BC146767 AAI46768 BM052719 BM455812 BX648643 D87072 BAA13241 DA940867 U52191 AAC50806 U52365 AAC51135 XM_005262560 XP_005262617 XM_005262561 XP_005262618 XM_005262562 XP_005262619 XM_011531468 XP_011529770 XR_244571 XR_430568 XR_938609 XR_938610 NM_001146705 NP_001140177 NM_001146706 NP_001140178 NM_004653 NP_004644 |
Function | Histone demethylase that specifically demethylates 'Lys- 4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis. {ECO:0000269|PubMed:17320160, ECO:0000269|PubMed:17320162, ECO:0000269|PubMed:17351630}. |
Subcellular Location | Nucleus {ECO:0000305}. |
SmcY (C-14) - sc-83943 from Santa Cruz Biotechnology
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SmcY (G-18) - sc-83944 from Santa Cruz Biotechnology
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SmcY (H-96) - sc-98684 from Santa Cruz Biotechnology
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SmcY (K-17) - sc-83945 from Santa Cruz Biotechnology
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Anti-KDM5D / JARID1D Antibody (aa1440-1490) - LS-C89158 from LifeSpan Bioscience
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Anti-KDM5D / JARID1D Antibody (aa1490-1540) - LS-C288533 from LifeSpan Bioscience
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Anti-KDM5D / JARID1D Antibody (aa1490-1540) IHC-plus™ - LS-B6872 from LifeSpan Bioscience
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Jarid1D Antibody - NBP2-33548 from Novus Biologicals
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Jarid1D Antibody - 22240002 from Novus Biologicals
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Jarid1D Antibody - NB100-93292 from Novus Biologicals
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Jarid1D Antibody - NBP2-38898 from Novus Biologicals
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Anti-SMCY (C-term) antibody produced in rabbit - SAB1300510 from Sigma-Aldrich
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Anti-KDM5D antibody produced in rabbit - HPA049086 from Sigma-Aldrich
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KDM5D antibody - GTX129826 from GeneTex
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JARID1D antibody - 22739-1-AP from Acris Antibodies
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JARID1D (C-term) antibody - AP60001PU-L from Acris Antibodies
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JARID1D (C-term) antibody - AP60001PU-N from Acris Antibodies
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JARID1D antibody - H00008284-M03 from Acris Antibodies
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KDM5D antibody - 22739-1-AP from Proteintech Group
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JARID1D/SMCY Antibody - A301-751A from Bethyl Labs
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Anti-KDM5D (C-terminal) polyclonal antibody - DPABT-H30376 from Creative Diagnostics
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SMCY - MBS620800 from MyBioSource
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SMCY - MBS622896 from MyBioSource
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SMCY - MBS629696 from MyBioSource
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SMCY/JARID1D, Polyclonal Antibody - MBS691073 from MyBioSource
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