Gene Symbol | KDM5D |
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Entrez Gene | 8284 |
Alt Symbol | HY, HYA, JARID1D, SMCY |
Species | Human |
Gene Type | protein-coding |
Description | lysine (K)-specific demethylase 5D |
Other Description | H-Y|Jumonji, AT rich interactive domain 1D (RBP2-like)|SMC homolog, Y chromosome|Smcy homolog, Y-linked|histocompatibility Y antigen|histone demethylase JARID1D|jumonji/ARID domain-containing protein 1D|lysine-specific demethylase 5D|protein SmcY|selected mouse cDNA on Y, human homolog of |
Swissprots | A6H8V7 Q9BY66 Q9HCU1 Q92809 B7ZLX1 A2RU19 Q92509 |
Accessions | AAG00951 AAK27839 EAW54663 EAW54664 Q9BY66 AA864889 AK095923 AK127269 BAG54468 AK304027 BAG64942 BC011053 BC132721 AAI32722 BC144101 BC144102 AAI44103 BC146767 AAI46768 BM052719 BM455812 BX648643 D87072 BAA13241 DA940867 U52191 AAC50806 U52365 AAC51135 XM_005262560 XP_005262617 XM_005262561 XP_005262618 XM_005262562 XP_005262619 XM_011531468 XP_011529770 XR_244571 XR_430568 XR_938609 XR_938610 NM_001146705 NP_001140177 NM_001146706 NP_001140178 NM_004653 NP_004644 |
Function | Histone demethylase that specifically demethylates 'Lys- 4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis. {ECO:0000269|PubMed:17320160, ECO:0000269|PubMed:17320162, ECO:0000269|PubMed:17351630}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Jarid1D Recombinant Protein - P4717 from Novus Biologicals
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JARID1D (His-tag) - AR60001PU-N from Acris Antibodies
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JARID1D - H00008284-Q01-10 from Acris Antibodies
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JARID1D - H00008284-Q01-25 from Acris Antibodies
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KDM5D fusion protein - ag18690 from Proteintech Group
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SMCY (950-960) (human) - 78951 from NeoScientific
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Recombinant Human Lysine-specific demethylase 5D(KDM5D) ,partial - CSB-YP863151HU CSB-EP863151HU CSB-BP863151HU CSB-MP863151HU from Cusabio
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Recombinant Pan troglodytes Lysine-specific demethylase 5D(KDM5D) ,partial - CSB-YP713618EQV CSB-EP713618EQV CSB-BP713618EQV CSB-MP713618EQV from Cusabio
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SMCY, Peptide - MBS633736 from MyBioSource
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Recombinant Human KDM5D, His tagged - CS414 from Cell Science
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Recombinant Human MAP2K6 Active GST - CSI12120 from Cell Science
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Jarid1D Protein - NBP2-33548PEP from Novus Biologicals
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Jarid1D Protein - NBP2-38898PEP from Novus Biologicals
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SMCY (950-960) - abx265114 from Abbexa
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JARID1D-KDM5DSMCY-Antibody-C-term-Blocking-peptide - BP1045b from Abgent, a WuXi AppTec company
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SMCY (950-960) (human) - H08002 from Creative Peptides
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KDM5D Peptide, Human - M34GP08053H from Creative Peptides
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SMCY (950-960) (Human) - CCP2895 from Cohesion Biosciences
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Lysine-specific demethylase 5D (KDM5D), partial, Recombinant Protein - MBS1298912 from MyBioSource
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SMCY/JARID1D, Recombinant Protein - MBS692086 from MyBioSource
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