Gene Symbol | JPH4 |
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Entrez Gene | 84502 |
Alt Symbol | JP4, JPHL1 |
Species | Human |
Gene Type | protein-coding |
Description | junctophilin 4 |
Other Description | JP-4|junctophilin like 1|junctophilin-4|junctophilin-like 1 protein |
Swissprots | Q8ND44 D3DS53 Q96JJ6 Q96DQ0 |
Accessions | EAW66135 EAW66139 Q96JJ6 AB058734 BAB47460 AK055345 BAB70905 AK091572 AK290511 BAF83200 AK304514 BAH14203 AL834411 CAD39073 AY344068 AAS47836 BC055429 AAH55429 BC109228 DA108605 NM_001146028 NP_001139500 NM_032452 NP_115828 |
Function | Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH4 is brain- specific and appears to have an active role in certain neurons involved in motor coordination and memory (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Note=Localized predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic reticulum membrane, while the N-terminal part associates with the plasma membrane (By similarity). {ECO:0000250}. |
Junctophilin-4 (S-15) - sc-162971 from Santa Cruz Biotechnology
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Anti-JPH4 antibody - ab79067 from Abcam
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Anti-JPH4 antibody - ab79077 from Abcam
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Anti-JPH4 Antibody (Internal) IHC-plus⢠- LS-B4166 from LifeSpan Bioscience
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Anti-JPH4 Antibody (aa510-559) - LS-C201747 from LifeSpan Bioscience
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Anti-JPH4 Antibody (C-Terminus) - LS-C82885 from LifeSpan Bioscience
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Anti-JPH4 Antibody (aa111-160) - LS-C205771 from LifeSpan Bioscience
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JPH4 Antibody - NBP2-41094 from Novus Biologicals
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JPH4 Antibody - NBP2-41095 from Novus Biologicals
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JPH4 Antibody - NBP2-41093 from Novus Biologicals
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Junctophilin 4 Polyclonal Antibody - bs-11084R from Bioss
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Junctophilin 4 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11084R-A350 from Bioss
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Junctophilin 4 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11084R-A488 from Bioss
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Junctophilin 4 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11084R-A555 from Bioss
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Junctophilin 4 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11084R-A647 from Bioss
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Junctophilin 4 Polyclonal Antibody, Cy3 Conjugated - bs-11084R-Cy3 from Bioss
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Junctophilin 4 Polyclonal Antibody, Cy5 Conjugated - bs-11084R-Cy5 from Bioss
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Junctophilin 4 Polyclonal Antibody, Cy5.5 Conjugated - bs-11084R-Cy5.5 from Bioss
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Junctophilin 4 Polyclonal Antibody, Cy7 Conjugated - bs-11084R-Cy7 from Bioss
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Junctophilin 4 Polyclonal Antibody, FITC Conjugated - bs-11084R-FITC from Bioss
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Junctophilin 4 Polyclonal Antibody, Biotin Conjugated - bs-11084R-Biotin from Bioss
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Junctophilin 4 Polyclonal Antibody, HRP Conjugated - bs-11084R-HRP from Bioss
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Anti-JPH2 (ab1) antibody produced in rabbit - PRS4919 from Sigma-Aldrich
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Anti-JPH4 (ab1) antibody produced in rabbit - PRS4923 from Sigma-Aldrich
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JPH4 Antibody - C-terminal region (ARP60269_P050) - ARP60269_P050 from Aviva Systems Biology
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