Gene Symbol | JPH4 |
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Entrez Gene | 84502 |
Alt Symbol | JP4, JPHL1 |
Species | Human |
Gene Type | protein-coding |
Description | junctophilin 4 |
Other Description | JP-4|junctophilin like 1|junctophilin-4|junctophilin-like 1 protein |
Swissprots | Q8ND44 D3DS53 Q96JJ6 Q96DQ0 |
Accessions | EAW66135 EAW66139 Q96JJ6 AB058734 BAB47460 AK055345 BAB70905 AK091572 AK290511 BAF83200 AK304514 BAH14203 AL834411 CAD39073 AY344068 AAS47836 BC055429 AAH55429 BC109228 DA108605 NM_001146028 NP_001139500 NM_032452 NP_115828 |
Function | Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH4 is brain- specific and appears to have an active role in certain neurons involved in motor coordination and memory (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Note=Localized predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic reticulum membrane, while the N-terminal part associates with the plasma membrane (By similarity). {ECO:0000250}. |
JPH4 peptide - ab110077 from Abcam
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JPH4 Antibody Blocking Peptide - LS-E30613 from LifeSpan Bioscience
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JPH4 Antibody Blocking Peptide - LS-E30617 from LifeSpan Bioscience
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JPH4 Peptide - GTX85362-PEP from GeneTex
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JPH4 Peptide - GTX85365-PEP from GeneTex
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Junctophilin-4 / JPH4 Control Peptide - AP30472CP-N from Acris Antibodies
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Junctophilin-4 / JPH4 Control Peptide - AP30473CP-N from Acris Antibodies
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JPH4 Peptide - 4933P from ProSci
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JPH4 Peptide - 4923P from ProSci
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Recombinant Human Junctophilin-4(JPH4) - CSB-YP850319HU CSB-EP850319HU CSB-BP850319HU CSB-MP850319HU from Cusabio
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Junctophilin-4 / JPH4 - TP308221 from Acris Antibodies
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JPH4 Peptide, Human - M34GP07873H from Creative Peptides
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JPH4 Recombinant Protein Antigen - NBP2-54969PEP from Novus Biologicals
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Junctophilin-4 (JPH4), Recombinant Protein - MBS1299789 from MyBioSource
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Recombinant Human JPH4 Protein, MYC/DDK-tagged - JPH4-784H from Creative Biomart
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