Gene Symbol | INTU |
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Entrez Gene | 27152 |
Alt Symbol | INT, PDZD6, PDZK6 |
Species | Human |
Gene Type | protein-coding |
Description | inturned planar cell polarity protein |
Other Description | PDZ domain containing 6|PDZ domain-containing protein 6|homolog of inturned|inturned planar cell polarity effector homolog|protein inturned |
Swissprots | Q4W5I8 D6RBT4 Q86V55 A1L4N5 Q9ULD6 D6RAE6 |
Accessions | AAY41002 CAK32347 EAX05201 EAX05202 Q9ULD6 AB033110 BAA86598 AK123320 BAG53888 AK291481 BAF84170 BC051698 AAH51698 BC130611 AAI30612 BC144182 DB195553 DB302901 HQ234310 HQ234311 HQ258681 ADR83432 XM_011531844 XP_011530146 XM_011531845 XP_011530147 XM_011531846 XP_011530148 XM_011531847 XP_011530149 XM_011531848 XP_011530150 XM_011531849 XP_011530151 XM_011531850 XP_011530152 XM_011531851 XP_011530153 XR_938720 NM_015693 NP_056508 |
Function | Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cell surface {ECO:0000250}. Note=Enriched at the apical surface in ciliated cells. {ECO:0000250}. |
INTU (D-14) - sc-164690 from Santa Cruz Biotechnology
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INTU (E-14) - sc-164691 from Santa Cruz Biotechnology
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INTU (L-13) - sc-164692 from Santa Cruz Biotechnology
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Anti-LMO1 antibody - ab137599 from Abcam
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Anti-LMO1 antibody - C-terminal - ab136322 from Abcam
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Anti-PDZD6 antibody - ab122354 from Abcam
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Anti-INTU Antibody (aa816-865) - LS-C169884 from LifeSpan Bioscience
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INTU Antibody - NBP1-81420 from Novus Biologicals
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INTU Antibody - H00027152-B01 from Novus Biologicals
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PDZD6 Polyclonal Antibody - bs-9041R from Bioss
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Anti-INTU antibody produced in rabbit - HPA036714 from Sigma-Aldrich
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Anti-PDZD6 antibody produced in mouse - SAB1400498 from Sigma-Aldrich
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INTU Antibody - C-terminal region (ARP67141_P050) - ARP67141_P050 from Aviva Systems Biology
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INTU antibody - GTX120239 from GeneTex
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INTU / PDZD6 antibody - 24914-1-AP from Acris Antibodies
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INTU / PDZD6 antibody - H00027152-B01 from Acris Antibodies
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INTU / PDZD6 antibody - H00027152-B01P from Acris Antibodies
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INTU antibody - 24914-1-AP from Proteintech Group
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PDZD6, Polyclonal Antibody - MBS6008288 from MyBioSource
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Anti-INTU (aa 278-368) polyclonal antibody - DPABH-20651 from Creative Diagnostics
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Anti-INTU monoclonal antibody - DCABH-200737 from Creative Diagnostics
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INTU Polyclonal Antibody - PA5-35900 from Thermo Fisher Scientific
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PDZD6 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-9041R-A350 from Bioss
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PDZD6 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-9041R-A488 from Bioss
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PDZD6 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-9041R-A555 from Bioss
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