INTU

Gene Symbol INTU
Entrez Gene 27152
Alt Symbol INT, PDZD6, PDZK6
Species Human
Gene Type protein-coding
Description inturned planar cell polarity protein
Other Description PDZ domain containing 6|PDZ domain-containing protein 6|homolog of inturned|inturned planar cell polarity effector homolog|protein inturned
Swissprots Q4W5I8 D6RBT4 Q86V55 A1L4N5 Q9ULD6 D6RAE6
Accessions AAY41002 CAK32347 EAX05201 EAX05202 Q9ULD6 AB033110 BAA86598 AK123320 BAG53888 AK291481 BAF84170 BC051698 AAH51698 BC130611 AAI30612 BC144182 DB195553 DB302901 HQ234310 HQ234311 HQ258681 ADR83432 XM_011531844 XP_011530146 XM_011531845 XP_011530147 XM_011531846 XP_011530148 XM_011531847 XP_011530149 XM_011531848 XP_011530150 XM_011531849 XP_011530151 XM_011531850 XP_011530152 XM_011531851 XP_011530153 XR_938720 NM_015693 NP_056508
Function Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Cell surface {ECO:0000250}. Note=Enriched at the apical surface in ciliated cells. {ECO:0000250}.

INTU CRISPR/Cas9 KO Plasmid (h) - sc-411970 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

INTU HDR Plasmid (h) - sc-411970-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

INTU Double Nickase Plasmid (h) - sc-411970-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

INTU Double Nickase Plasmid (h2) - sc-411970-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

INTU CRISPR Activation Plasmid (h) - sc-411970-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

INTU CRISPR Activation Plasmid (h2) - sc-411970-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

INTU Lentiviral Activation Particles (h) - sc-411970-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

INTU Lentiviral Activation Particles (h2) - sc-411970-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

INTU siRNA (h) - sc-89118 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

INTU shRNA Plasmid (h) - sc-89118-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

INTU shRNA (h) Lentiviral Particles - sc-89118-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU075521 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10722 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10722 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03156 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03156

INTU siRNA (Human) - CRH8996 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

INTU - MBS8228024 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human INTU (NM_015693.3) - SHH320061 from Creative biogene

Category siRNA
Species Reactivities Human

Human INTU siRNA - orb269498 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

INTU shRNA Plasmid (Human) - CHH8996 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

INTU miRNA 3'UTR clone - MiUTR3H-11356 from Creative biogene

Species Reactivities Human
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