INTU

Gene Symbol	INTU
Entrez Gene	27152
Alt Symbol	INT, PDZD6, PDZK6
Species	Human
Gene Type	protein-coding
Description	inturned planar cell polarity protein
Other Description	PDZ domain containing 6|PDZ domain-containing protein 6|homolog of inturned|inturned planar cell polarity effector homolog|protein inturned
Swissprots	Q4W5I8 D6RBT4 Q86V55 A1L4N5 Q9ULD6 D6RAE6
Accessions	AAY41002 CAK32347 EAX05201 EAX05202 Q9ULD6 AB033110 BAA86598 AK123320 BAG53888 AK291481 BAF84170 BC051698 AAH51698 BC130611 AAI30612 BC144182 DB195553 DB302901 HQ234310 HQ234311 HQ258681 ADR83432 XM_011531844 XP_011530146 XM_011531845 XP_011530147 XM_011531846 XP_011530148 XM_011531847 XP_011530149 XM_011531848 XP_011530150 XM_011531849 XP_011530151 XM_011531850 XP_011530152 XM_011531851 XP_011530153 XR_938720 NM_015693 NP_056508
Function	Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Cell surface {ECO:0000250}. Note=Enriched at the apical surface in ciliated cells. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PDZD6 full length protein - ab162097 from Abcam Category Protein Source Wheat germ Species Human

INTU Antibody Blocking Peptide - LS-E24323 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human INTU Protein - H00027152-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

INTU / PDZD6 - H00027152-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

INTU / PDZD6 - H00027152-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

INTU fusion protein - ag19313 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Protein inturned(INTU) ,partial - CSB-YP891544HU CSB-EP891544HU CSB-BP891544HU CSB-MP891544HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

INTU / PDZD6 - TP318556 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

INTU Recombinant Protein Antigen - NBP1-81420PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

INTU Recombinant Protein Antigen - NBP2-48663PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

PDZD6-Antibody-C-term-Blocking-peptide - BP5786b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

INTU Peptide, Human - M34GP07694H from Creative Peptides Category Peptide Source Synthetic. Species Human

INT/BCIP, Recombinant Protein - MBS546474 from MyBioSource Category Protein Prices $130.00 Sizes 5 preps

Protein inturned (INTU), partial, Recombinant Protein - MBS1358232 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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