Gene Symbol | APOA5 |
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Entrez Gene | 116519 |
Alt Symbol | APOAV, RAP3 |
Species | Human |
Gene Type | protein-coding |
Description | apolipoprotein A-V |
Other Description | apo-AV|apolipoprotein A5|regeneration-associated protein 3 |
Swissprots | Q9UBJ3 Q6UWK9 Q6Q788 B0YIV9 Q3MIK6 |
Accessions | AAQ91808 AAS68229 ACA05937 ACA05938 AIY32613 CAC24995 CAD88066 EAW67269 EAW67270 Q6Q788 AF202889 AAF25661 AF202890 AAF25662 AK292739 BAF85428 AK308047 AK315229 BAG37658 AY358749 AAQ89109 BC101787 AAI01788 BC101789 AAI01790 DA641693 DB184692 NM_001166598 NP_001160070 NM_052968 NP_443200 |
Function | Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and a inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate) (By similarity). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages. {ECO:0000250, ECO:0000269|PubMed:11588264, ECO:0000269|PubMed:12899628, ECO:0000269|PubMed:15528295}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:12810715}. |
Tissue Specificity | Liver and plasma. {ECO:0000269|PubMed:11577099, ECO:0000269|PubMed:11588264, ECO:0000269|PubMed:15528295}. |
Top Pathways | PPAR signaling pathway |
Human Apolipoprotein A V full length protein - ab113861 from Abcam
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Human Apolipoprotein A V full length protein - ab165112 from Abcam
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Human Apolipoprotein A V full length protein - ab174391 from Abcam
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Human Apolipoprotein A V peptide - ab78151 from Abcam
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APOA5 / Apolipoprotein A V Antibody Blocking Peptide - LS-E8931 from LifeSpan Bioscience
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APOA5 / Apolipoprotein A V Antibody Blocking Peptide - LS-E26396 from LifeSpan Bioscience
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APOA5 / Apolipoprotein A V Antibody Blocking Peptide - LS-E31108 from LifeSpan Bioscience
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Apolipoprotein A5 Recombinant Protein - H00116519-P01 from Novus Biologicals
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Recombinant Human Apolipoprotein A5 Protein - NBP2-22689 from Novus Biologicals
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Apolipoprotein A5 Peptide - P2498 from Novus Biologicals
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APOA5-Antibody-N-term-Blocking-Peptide - BP7412a from Abgent, a WuXi AppTec company
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Apolipoprotein A5 blocking peptide - GTX88628-PEP from GeneTex
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Human APOA5 protein - orb167902 from Biorbyt
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Human APOD protein - orb168533 from Biorbyt
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Human APOA5 protein - orb191040 from Biorbyt
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ApoA5 protein (His tag) - 80R-3609 from Fitzgerald
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Human Apolipoprotein A5 Protein - abx065409 from Abbexa
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Apolipoprotein A V Peptide - AC21-1232-P from Abcore
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Apolipoprotein A V / ApoA5 (24-366, His-tag) - AR51296PU-N from Acris Antibodies
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Apolipoprotein A V / ApoA5 (24-366, His-tag) - AR51296PU-S from Acris Antibodies
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Apolipoprotein A V / ApoA5 - H00116519-P01-10 from Acris Antibodies
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Apolipoprotein A V / ApoA5 - H00116519-P01-25 from Acris Antibodies
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Apolipoprotein A V / ApoA5 control peptide - AP26164CP-N from Acris Antibodies
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Apolipoprotein A-V, Human Recombinant, HEK - 228-11897-1 from RayBiotech
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Recombinant Apolipoprotein A-V Human - 228-11897-2 from RayBiotech
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